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BMC Biochemistry


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  1. Content type: Research article

    Human phospholipid scramblase 1 (hPLSCR1) was initially identified as a Ca2+ dependent phospholipid translocator involved in disrupting membrane asymmetry. Recent reports revealed that hPLSCR1 acts as a multifunc...

    Authors: Ulaganathan Sivagnanam, Shweta Narayana Murthy and Sathyanarayana N. Gummadi

    Citation: BMC Biochemistry 2016 17:10

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  2. Content type: Research article

    Dnmt3a is a DNA methyltransferase that establishes de novo DNA methylation in mammals. The structure of the Dnmt3a C-terminal domain is similar to the bacterial M. HhaI enzyme, a well-studied prokaryotic DNA meth...

    Authors: Olga V. Lukashevich, Natalia A. Cherepanova, Renata Z. Jurkovska, Albert Jeltsch and Elizaveta S. Gromova

    Citation: BMC Biochemistry 2016 17:7

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  3. Content type: Research article

    Thauera linaloolentis 47Lol uses the tertiary monoterpene alcohol (R,S)-linalool as sole carbon and energy source under denitrifying conditions. The conversion of linalool to geraniol ...

    Authors: Robert Marmulla, Barbara Šafarić, Stephanie Markert, Thomas Schweder and Jens Harder

    Citation: BMC Biochemistry 2016 17:6

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  4. Content type: Research article

    1,2-Dichlorobenzene (1,2-DCB) is a benzene-derived molecule with two Cl atoms that is commonly utilized in the synthesis of pesticides. 1,2-DCB can be absorbed by living creatures and its effects on naturally-...

    Authors: Javier Vargas-Medrano, Jorge A. Sierra-Fonseca and Luis F. Plenge-Tellechea

    Citation: BMC Biochemistry 2016 17:5

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  5. Content type: Research article

    The use of metagenomics in enzyme discovery constitutes a powerful approach to access to genomes of unculturable community of microorganisms and isolate novel valuable biocatalysts for use in a wide range of b...

    Authors: Concetta De Santi, Bjørn Altermark, Marcin Miroslaw Pierechod, Luca Ambrosino, Donatella de Pascale and Nils-Peder Willassen

    Citation: BMC Biochemistry 2016 17:1

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  6. Content type: Research article

    Destabilase-Lysozyme (mlDL) is a multifunctional i-type enzyme that has been found in the secretions from the salivary glands of medicinal leeches. mlDL has been shown to exhibit isopeptidase, muramidase and a...

    Authors: Alexey S. Kurdyumov, Valentin A. Manuvera, Isolda P. Baskova and Vassili N. Lazarev

    Citation: BMC Biochemistry 2015 16:27

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  7. Content type: Research article

    β-Mannans are abundant and diverse plant structural and storage polysaccharides. Certain human gut microbiota members including health-promoting Bifidobacterium spp. catabolize dietary mannans. Little insight is ...

    Authors: Johan Morrill, Evelina Kulcinskaja, Anna Maria Sulewska, Sampo Lahtinen, Henrik Stålbrand, Birte Svensson and Maher Abou Hachem

    Citation: BMC Biochemistry 2015 16:26

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  8. Content type: Research article

    eIF3f is a multifunctional protein capable of interacting with proteins involved in different cellular processes, such as protein synthesis, DNA repair, and viral mRNA edition. In human cells, eIF3f is related...

    Authors: Mario Javier Gutiérrez-Fernández, Ana Edith Higareda-Mendoza, César Adrián Gómez-Correa and Marco Aurelio Pardo-Galván

    Citation: BMC Biochemistry 2015 16:25

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  9. Content type: Research article

    The defensive capacities of plant protease Inhibitors (PI) rely on inhibition of proteases in insect guts or those secreted by microorganisms; and also prevent uncontrolled proteolysis and offer protection aga...

    Authors: V D Sirisha Gandreddi, Vijaya Rachel Kappala, Kunal Zaveri and Kiranmayi Patnala

    Citation: BMC Biochemistry 2015 16:23

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  10. Content type: Research article

    Aberrant mitochondrial function, including excessive reactive oxygen species (ROS) production, has been implicated in the pathogenesis of human diseases. The use of mitochondrial inhibitors to ascertain the si...

    Authors: Aaron M. Gusdon, Gabriel A. Fernandez-Bueno, Stephanie Wohlgemuth, Jenelle Fernandez, Jing Chen and Clayton E. Mathews

    Citation: BMC Biochemistry 2015 16:22

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  11. Content type: Research article

    Saccharomyces cerevisiae triosephosphate isomerase (yTIM) is a dimeric protein that shows noncoincident unfolding and refolding transitions (hysteresis) in temperature scans, a phenome...

    Authors: Ariana Labastida-Polito, Georgina Garza-Ramos, Menandro Camarillo-Cadena, Rafael A. Zubillaga and Andrés Hernández-Arana

    Citation: BMC Biochemistry 2015 16:20

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  12. Content type: Research article

    Members of Rhizopus species are the most common cause of mucormycosis, a rare but often fatal fungal infection. Host induced pathogen apoptosis and pathogen induced host cell apoptosis are often involved in funga...

    Authors: Manoj Saxena, Rohit Kumar Sharma, Josell Ramirez-Paz, Arthur D. Tinoco and Kai Griebenow

    Citation: BMC Biochemistry 2015 16:21

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    The Erratum to this article has been published in BMC Biochemistry 2016 17:3

  13. Content type: Research article

    Dual-specificity phosphatase-5 (DUSP5) plays a central role in vascular development and disease. We present a p-nitrophenol phosphate (pNPP) based enzymatic assay to screen for inhibitors of the phosphatase domai...

    Authors: Terrence S. Neumann, Elise A. Span, Kelsey S. Kalous, Robert Bongard, Adam Gastonguay, Michael A. Lepley, Raman G. Kutty, Jaladhi Nayak, Chris Bohl, Rachel G. Lange, Majher I. Sarker, Marat R. Talipov, Rajendra Rathore, Ramani Ramchandran and Daniel S. Sem

    Citation: BMC Biochemistry 2015 16:19

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  14. Content type: Research article

    Computational protein design is a rapidly maturing field within structural biology, with the goal of designing proteins with custom structures and functions. Such proteins could find widespread medical and ind...

    Authors: Deepesh Nagarajan, Geeta Deka and Megha Rao

    Citation: BMC Biochemistry 2015 16:18

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  15. Content type: Research article

    Green fluorescent protein (GFP) and its derivative fluorescent proteins (FPs) are among the most commonly used reporter systems for studying gene expression and protein interaction in biomedical research. Most...

    Authors: Shu-su Liu, Xuan Wei, Xue Dong, Liang Xu, Jia Liu and Biao Jiang

    Citation: BMC Biochemistry 2015 16:17

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  16. Content type: Research article

    Potassium channels play a fundamental role in resetting the resting membrane potential of excitable cells. Determining the intracellular trafficking and localization mechanisms of potassium channels provides a...

    Authors: John M. Spear, Dolly Al Koborssy, Austin B. Schwartz, Adam J. Johnson, Anjon Audhya, Debra A. Fadool and Scott M. Stagg

    Citation: BMC Biochemistry 2015 16:16

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  17. Content type: Methodology article

    The 5′-triphosphorylated, 2′-5′-linked oligoadenylate polyribonucleotides (2-5As) are central to the interferon-induced antiviral 2-5A system. The 2-5As bind and activate the RNase L, an endoRNase degrading vi...

    Authors: Jesper Buchhave Poulsen, Karina Hansen Kjær, Just Justesen and Pia Møller Martensen

    Citation: BMC Biochemistry 2015 16:15

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  18. Content type: Research article

    The activity of eukaryotic DNA polymerase delta (Pol δ) plays an essential role in genome stability through its effects on DNA replication and repair. The p125 catalytic subunit of Pol δ is encoded by POLD1 gene ...

    Authors: Jing Song, Ping Hong, Chengeng Liu, Yueqi Zhang, Jinling Wang and Peichang Wang

    Citation: BMC Biochemistry 2015 16:14

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  19. Content type: Research article

    To investigate the roles of androgen receptor (AR) in epithelial- mesenchymal transition (EMT) in human prostate cancer stem progenitor (S/P) cells isolated from LNCaP cell line.

    Authors: Ma Zhifang, Wei Liang, Zhang Wei, Hao Bin, Tu Rui, Wu Nan and Zhang Shuhai

    Citation: BMC Biochemistry 2015 16:13

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  20. Content type: Research article

    Fidelity of DNA polymerases can be influenced by cation co-factors. Physiologically, Mg2+ is used as a co-factor by HIV reverse transcriptase (RT) to perform catalysis; however, alternative cations including Mn2+

    Authors: Vasudevan Achuthan and Jeffrey J DeStefano

    Citation: BMC Biochemistry 2015 16:12

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2016 Journal Metrics

  • Citation Impact
    1.481 - 2-year Impact Factor
    1.696 - 5-year Impact Factor
    0.432 - Source Normalized Impact per Paper (SNIP)
    0.630 - SCImago Journal Rank (SJR)

    1758 Usage Factor

    Social Media Impact
    18 mentions