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Featured article: An evolutionary encounter between tRNA and myelin maturation
tRNA splicing is an essential process in the maturation of eukaryotic pre-tRNA molecules. This study shows that tRNA healing enzymes from yeast and lancelet share structural and functional properties with members of the 2H-phosphoesterase superfamily, in particular the vertebrate myelin enzyme CNPase. While domain organization has been conserved, functions of the individual domains may have been altered or lost during evolution.
Featured article: Essential residues of Dnmt3a
The conserved residues of Dnmt3a, R200 and R202, are essential for methylation activity. They are involved in positioning of the flipped target base and in creating and stabilizing of the transient covalent intermediate of the methylation reaction.
Articles
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Association of TM6SF2 rs58542926 gene polymorphism with the risk of non-alcoholic fatty liver disease and colorectal adenoma in Chinese Han population
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The active role of the transcription factor Sp1 in NFATc2-mediated gene regulation in pancreatic cancer
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Role of the highly conserved G68 residue in the yeast phosphorelay protein Ypd1: implications for interactions between histidine phosphotransfer (HPt) and response regulator proteins
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Up-regulation of DcR3 in microbial toxins-stimulated HUVECs involves NF-κB signalling
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Determination of carbohydrate-deficient transferrin in a Han Chinese population
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Expression and characterization of a β-fructofuranosidase from the parasitic protist Trichomonas vaginalis
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Soybean peroxidase-mediated degradation of an azo dye– a detailed mechanistic study
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Simple spectrophotometric assay for measuring catalase activity in biological tissues
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Digested wheat gluten inhibits binding between leptin and its receptor
Aims and scope
BMC Biochemistry is an open access, peer-reviewed journal that considers articles on all aspects of biochemical processes, including the structure, function and dynamics of metabolic pathways, supramolecular complexes, enzymes, proteins, nucleic acids and small molecular components of organelles, cells and tissues.
Editor
- Alison Cuff, BioMed Central
Section Editors
- Sabato D'Auria, CNR
- Chris Grant, University of Manchester
- Albert Jeltsch, Universität Stuttgart
- Joel Weiner, University of Alberta
Albert Jeltsch, Section Editor
Prof. Jeltsch is professor of Biochemistry at the University Stuttgart. His research group is leading in the biochemical study of bacterial DNA methyltransferases and mammalian DNA methyltransferases. Their work has been published in more than 200 papers. Prof. Jeltsch joined the board of BMC Biochemistry in 2009.
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2017 Journal Metrics
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Citation Impact
1.595 - 2-year Impact Factor
1.515 - 5-year Impact Factor
0.503 - Source Normalized Impact per Paper (SNIP)
0.708 - SCImago Journal Rank (SJR)Usage
188,146 downloadsSocial Media Impact
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