BMC Biochemistry

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Featured article: An evolutionary encounter between tRNA and myelin maturation

tRNA splicing is an essential process in the maturation of eukaryotic pre-tRNA molecules. This study shows that tRNA healing enzymes from yeast and lancelet share structural and functional properties with members of the 2H-phosphoesterase superfamily, in particular the vertebrate myelin enzyme CNPase. While domain organization has been conserved, functions of the individual domains may have been altered or lost during evolution.

Featured article: Essential residues of Dnmt3a

The conserved residues of Dnmt3a, R200 and R202, are essential for methylation activity. They are involved in positioning of the flipped target base and in creating and stabilizing of the transient covalent intermediate of the methylation reaction.

Content type: Research article
| 6 February 2019

Association of TM6SF2 rs58542926 gene polymorphism with the risk of non-alcoholic fatty liver disease and colorectal adenoma in Chinese Han population

Authors: Yuan Li, Shousheng Liu, Yuqiang Gao, Huan Ma, Shuhui Zhan, Yan Yang, Yongning Xin and Shiying Xuan
Content type: Research article
| 29 January 2019

The active role of the transcription factor Sp1 in NFATc2-mediated gene regulation in pancreatic cancer

Authors: Manuela Malsy, Bernhard Graf and Katrin Almstedt
Content type: Research article
| 21 January 2019

Role of the highly conserved G68 residue in the yeast phosphorelay protein Ypd1: implications for interactions between histidine phosphotransfer (HPt) and response regulator proteins

Authors: Emily N. Kennedy, Skyler D. Hebdon, Smita K. Menon, Clay A. Foster, Daniel M. Copeland, Qingping Xu, Fabiola Janiak-Spens and Ann H. West
Content type: Research article
| 27 December 2018

Up-regulation of DcR3 in microbial toxins-stimulated HUVECs involves NF-κB signalling

Authors: Yanqiang Hou, Dongyu Liang, Yang Liu, Hongwei Chen and Xiaoli Lou
Content type: Methodology article
| 18 December 2018

Soluble expression of recombinant midgut zymogen (native propeptide) proteases from the Aedes aegypti Mosquito Utilizing E. coli as a host

Authors: James T. Nguyen, Jonathan Fong, Daniel Fong, Timothy Fong, Rachael M. Lucero, Jamie M. Gallimore, Olive E. Burata, Kamille Parungao and Alberto A. Rascón Jr

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Content type: Methodology article
| 27 February 2014

Determination of carbohydrate-deficient transferrin in a Han Chinese population

Authors: Binbin Song, Jing Zhu, Jiong Wu, Chunyan Zhang, Beili Wang, Baishen Pan and Wei Guo
Content type: Research article
| 28 June 2014

Expression and characterization of a β-fructofuranosidase from the parasitic protist Trichomonas vaginalis

Authors: Michael Dirkx, Michael P Boyer, Prajakta Pradhan, Andrew Brittingham and Wayne A Wilson
Content type: Research article
| 5 December 2013

Soybean peroxidase-mediated degradation of an azo dye– a detailed mechanistic study

Authors: Liaquat Ali, Rowdha Algaithi, Hosam M Habib, Usama Souka, Muhammad A Rauf and S Salman Ashraf
Content type: Research article
| 20 January 2015

Digested wheat gluten inhibits binding between leptin and its receptor

Authors: Tommy Jönsson, Ashfaque A Memon, Kristina Sundquist, Jan Sundquist, Stefan Olsson, Amarnadh Nalla, Mikael Bauer and Sara Linse
Content type: Methodology article
| 24 March 2005

A simplified method for analysis of polyunsaturated fatty acids

Authors: Jing X Kang and Jingdong Wang

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Aims and scope

BMC Biochemistry is an open access, peer-reviewed journal that considers articles on all aspects of biochemical processes, including the structure, function and dynamics of metabolic pathways, supramolecular complexes, enzymes, proteins, nucleic acids and small molecular components of organelles, cells and tissues.

Editor

Alison Cuff, BioMed Central

Section Editors

Sabato D'Auria, CNR
Chris Grant, University of Manchester
Albert Jeltsch, Universität Stuttgart
Joel Weiner, University of Alberta

Albert Jeltsch, Section Editor

Prof. Jeltsch is professor of Biochemistry at the University Stuttgart. His research group is leading in the biochemical study of bacterial DNA methyltransferases and mammalian DNA methyltransferases. Their work has been published in more than 200 papers. Prof. Jeltsch joined the board of BMC Biochemistry in 2009.

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Recruitment of pregnant women in randomized trials: What could hold us back?

18 March 2019
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13 March 2019
BMC Health Services Research: Editor picks of 2018

12 March 2019

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Get credit for your data

Featured article: An evolutionary encounter between tRNA and myelin maturation

Featured article: Essential residues of Dnmt3a

Articles

Association of TM6SF2 rs58542926 gene polymorphism with the risk of non-alcoholic fatty liver disease and colorectal adenoma in Chinese Han population

The active role of the transcription factor Sp1 in NFATc2-mediated gene regulation in pancreatic cancer

Role of the highly conserved G68 residue in the yeast phosphorelay protein Ypd1: implications for interactions between histidine phosphotransfer (HPt) and response regulator proteins

Up-regulation of DcR3 in microbial toxins-stimulated HUVECs involves NF-κB signalling

Soluble expression of recombinant midgut zymogen (native propeptide) proteases from the Aedes aegypti Mosquito Utilizing E. coli as a host

Determination of carbohydrate-deficient transferrin in a Han Chinese population

Expression and characterization of a β-fructofuranosidase from the parasitic protist Trichomonas vaginalis

Soybean peroxidase-mediated degradation of an azo dye– a detailed mechanistic study

Digested wheat gluten inhibits binding between leptin and its receptor

A simplified method for analysis of polyunsaturated fatty acids

Aims and scope

Editor

Section Editors

Albert Jeltsch, Section Editor

BMC Series blog

Recruitment of pregnant women in randomized trials: What could hold us back?

BMC Molecular and Cell Biology: one journal, one community, any organism

BMC Health Services Research: Editor picks of 2018

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