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Cellular and membrane biochemistry

Section edited by Chris Grant

This section incorporates all aspects of cellular and membrane biochemistry, including but not limited to: cell signaling and trafficking, chemical biology of the cell, membrane proteins and energy transduction, and macromolecular chemistry.

  1. Content type: Research article

    Sepsis is a severe condition characterised by the body’s systemic inflammatory response to infection. The specific sepsis-related biomarkers should be used in clinical diagnosis, therapeutic response monitorin...

    Authors: Yanqiang Hou, Dongyu Liang, Yang Liu, Hongwei Chen and Xiaoli Lou

    Citation: BMC Biochemistry 2018 19:13

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  2. Content type: Research article

    Corynebacterium urealyticum, a pathogenic, multidrug resistant member of the mycolata, is known as causative agent of urinary tract infections although it is a bacterium of the skin flora. This pathogenic bacteri...

    Authors: Narges Abdali, Farhan Younas, Samaneh Mafakheri, Karunakar R. Pothula, Ulrich Kleinekathöfer, Andreas Tauch and Roland Benz

    Citation: BMC Biochemistry 2018 19:3

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  3. Content type: Research article

    The mechanistic target of rapamycin complex 1 (mTORC1) is a well-conserved serine/threonine protein kinase that controls autophagy as well as many other processes such as protein synthesis, cell growth, and me...

    Authors: Hongjie Pan, Xiao-ping Zhong and Sunhee Lee

    Citation: BMC Biochemistry 2016 17:14

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  4. Content type: Research article

    eIF3f is a multifunctional protein capable of interacting with proteins involved in different cellular processes, such as protein synthesis, DNA repair, and viral mRNA edition. In human cells, eIF3f is related...

    Authors: Mario Javier Gutiérrez-Fernández, Ana Edith Higareda-Mendoza, César Adrián Gómez-Correa and Marco Aurelio Pardo-Galván

    Citation: BMC Biochemistry 2015 16:25

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  5. Content type: Research article

    Aberrant mitochondrial function, including excessive reactive oxygen species (ROS) production, has been implicated in the pathogenesis of human diseases. The use of mitochondrial inhibitors to ascertain the si...

    Authors: Aaron M. Gusdon, Gabriel A. Fernandez-Bueno, Stephanie Wohlgemuth, Jenelle Fernandez, Jing Chen and Clayton E. Mathews

    Citation: BMC Biochemistry 2015 16:22

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  6. Content type: Research article

    Potassium channels play a fundamental role in resetting the resting membrane potential of excitable cells. Determining the intracellular trafficking and localization mechanisms of potassium channels provides a...

    Authors: John M. Spear, Dolly Al Koborssy, Austin B. Schwartz, Adam J. Johnson, Anjon Audhya, Debra A. Fadool and Scott M. Stagg

    Citation: BMC Biochemistry 2015 16:16

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  7. Content type: Research article

    The Arabidopsis thaliana protein atTic20 is a key component of the protein import machinery at the inner envelope membrane of chloroplasts. As a component of the TIC complex, it is believed to form a preprotein-c...

    Authors: James H Campbell, Tuan Hoang, Masoud Jelokhani-Niaraki and Matthew D Smith

    Citation: BMC Biochemistry 2014 15:29

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  8. Content type: Research article

    Human telomerase reverse transcriptase (hTERT), the catalytic subunit of telomesase, is responsible for telomere maintenance and its reactivation is implicated in almost 90% human cancers. Recent evidences sho...

    Authors: Xu Cao, Chiou Mee Kong, Kanchi Madhu Mathi, Yoon Pin Lim, Valere Cacheux-Rataboul and Xueying Wang

    Citation: BMC Biochemistry 2014 15:17

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  9. Content type: Methodology article

    Secreted luciferases are highly useful bioluminescent reporters for cell-based assays and drug discovery. A variety of secreted luciferases from marine organisms have been described that harbor an N-terminal s...

    Authors: Christin Luft, Jamie Freeman, David Elliott, Nadia Al-Tamimi, Janos Kriston-Vizi, Jacob Heintze, Ida Lindenschmidt, Brian Seed and Robin Ketteler

    Citation: BMC Biochemistry 2014 15:14

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  10. Content type: Research article

    During EGFR internalization CIN85 bridges EGFR-Cbl complex, endocytic machinery and fusible membrane through the interactions of CIN85 with c-Cbl, endophilins and phosphatidic acid. These protein-protein and p...

    Authors: Xiudan Zheng, Jing Zhang and Kan Liao

    Citation: BMC Biochemistry 2014 15:13

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  11. Content type: Research article

    Organic solute carrier partner 1 (OSCP1) is known to facilitate the transport of various organic solutes into cells and reported to play a role in cell growth and cell differentiation. Moreover, OSCP1 is known...

    Authors: Nguyen Tho Huu, Hideki Yoshida, Takanari Umegawachi, Seiji Miyata and Masamitsu Yamaguchi

    Citation: BMC Biochemistry 2014 15:11

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  12. Content type: Research article

    Calciotropic hormones were thought to facilitate calcium transfer through active transcellular or passive paracellular pathway for calcium homeostasis. While calcium transport proteins such as CaBP-28 k, TRPV5...

    Authors: Inho Hwang, Eui-Ju Hong, Hyun Yang, Hong-Seok Kang, Changhwan Ahn, Beum-Soo An and Eui-Bae Jeung

    Citation: BMC Biochemistry 2014 15:6

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  13. Content type: Research article

    Autophagy is a cellular response to intracellular pathogens including mycobacteria and is induced by the direct inhibitors of mammalian target of Rapamycin (mTOR), a major negative regulator of autophagy. Auto...

    Authors: Alfred J Zullo, Kristen L Jurcic Smith and Sunhee Lee

    Citation: BMC Biochemistry 2014 15:4

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  14. Content type: Research article

    Transforming growth factor-betas (TGF-βs), including beta2 (TGF-β2), constitute a superfamily of multifunctional cytokines with important implications in morphogenesis, cell differentiation and tissue remodeli...

    Authors: Yan-Bin XiYang, Fang Wang, Bao-Jiang Qian, Ling You, Bing-Tuan Lu, Wei Zhang, Xiong-Zhi Quan, Wen-Ping Ge, Su Liu, Lian-Feng Zhang and Ting-Hua Wang

    Citation: BMC Biochemistry 2013 14:21

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  15. Content type: Research article

    Non-steroidal anti-inflammatory drugs (NSAIDs) —aspirin, naproxen, nimesulide, and piroxicam— lowered activation of type II cAMP-dependent protein kinase A (PKA-II) in isolated rat adipocytes, decreasing adren...

    Authors: Héctor Vázquez-Meza, Martha Zentella de Piña, Juan Pablo Pardo, Héctor Riveros-Rosas, Rafael Villalobos-Molina and Enrique Piña

    Citation: BMC Biochemistry 2013 14:13

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  16. Content type: Research article

    The androgen receptor (AR) is a member of the nuclear receptor (NR) superfamily of ligand-inducible DNA transcription factors, and is the major mediator of male sexual development, prostate growth and the path...

    Authors: Daniel Abankwa, Susan M Millard, Nick Martel, Catherine S Choong, Miao Yang, Lisa M Butler, Grant Buchanan, Wayne D Tilley, Nobuhide Ueki, Michael J Hayman and Gary M Leong

    Citation: BMC Biochemistry 2013 14:10

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  17. Content type: Research article

    Receptor tyrosine kinases (RTKs) are crucial components of signal transduction systems in multicellular animals. Surprisingly, numerous RTKs have been identified in the genomes of unicellular choanoflagellates...

    Authors: Kira P Schultheiss, Barbara P Craddock, Michael Tong, Markus Seeliger and W Todd Miller

    Citation: BMC Biochemistry 2013 14:4

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  18. Content type: Research article

    Presenilin-1 (PS1) is a transmembrane protein first discovered because of its association with familial Alzheimer’s disease. Mice with null mutations in PS1 die shortly after birth exhibiting multiple CNS and ...

    Authors: Rita De Gasperi, Miguel A Gama Sosa and Gregory A Elder

    Citation: BMC Biochemistry 2012 13:28

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  19. Content type: Research article

    Nasopharyngeal carcinoma (NPC) has a high metastatic feature. N,N-Dinitrosopiperazine (DNP) is involved in NPC metastasis, but its mechanism is not clear. The aim of this study is to reveal the pathogenesis of D...

    Authors: Yuejin Li, Na Liu, Damao Huang, Zhenlin Zhang, Zhengke Peng, Chaojun Duan, Xiaowei Tang, Gongjun Tan, Guangrong Yan, Wenhua Mei and Faqing Tang

    Citation: BMC Biochemistry 2012 13:25

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  20. Content type: Research article

    Phosphatase of regenerating liver-3 (PRL-3 or PTP4A3) has been implicated in controlling cancer cell proliferation, motility, metastasis, and angiogenesis. Deregulated expression of PRL-3 is highly correlated ...

    Authors: Wei Tian, Like Qu, Lin Meng, Caiyun Liu, Jian Wu and Chengchao Shou

    Citation: BMC Biochemistry 2012 13:22

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  21. Content type: Research article

    STAT1 is an essential transcription factor for interferon-γ-mediated gene responses. A distinct sumoylation consensus site (ψKxE) 702IKTE705 is localized in the C-terminal region of STAT1, where Lys703 is a targe...

    Authors: Juha Grönholm, Sari Vanhatupa, Daniela Ungureanu, Jouni Väliaho, Tuomo Laitinen, Jarkko Valjakka and Olli Silvennoinen

    Citation: BMC Biochemistry 2012 13:20

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  22. Content type: Research article

    Bird species show a high degree of variation in the composition of their preen gland waxes. For instance, galliform birds like chicken contain fatty acid esters of 2,3-alkanediols, while Anseriformes like goose o...

    Authors: Eva-Maria Biester, Janine Hellenbrand, Jens Gruber, Mats Hamberg and Margrit Frentzen

    Citation: BMC Biochemistry 2012 13:4

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  23. Content type: Research article

    ATP-binding cassette transporter A1 (ABCA1) mediates the lipidation of exchangeable apolipoproteins, the rate-limiting step in the formation of high density lipoproteins (HDL). We previously demonstrated that ...

    Authors: Mohammad A Hossain, Sereyrath Ngeth, Teddy Chan, Michael N Oda and Gordon A Francis

    Citation: BMC Biochemistry 2012 13:1

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  24. Content type: Research article

    Birds clean and lubricate their feathers with waxes that are produced in the uropygial gland, a holocrine gland located on their back above the tail. The type and the composition of the secreted wax esters are...

    Authors: Janine Hellenbrand, Eva-Maria Biester, Jens Gruber, Mats Hamberg and Margrit Frentzen

    Citation: BMC Biochemistry 2011 12:64

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2017 Journal Metrics

  • Citation Impact
    1.595 - 2-year Impact Factor
    1.515 - 5-year Impact Factor
    0.503 - Source Normalized Impact per Paper (SNIP)
    0.708 - SCImago Journal Rank (SJR)

    Usage 
    188,146 downloads

    Social Media Impact
    20 mentions

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