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Table 3 Significantly Up-Regulated Proteins in IAPP Treated Rin-5F Cells. The data were obtained from three independent experiments. To obtain the protein abundance ratio the amount of each protein in the IAPP treated cells was divided by its corresponding amount in the control cells (IAPP untreated cells). The corresponding ratios of all proteins were then averaged between the three experiments. If a specific protein was expressed in either untreated or IAPP treated samples, the missing value was replaced by the smallest amount that was potentially detected by the machine (0.1 femtomole). Differences between IAPP treated and un-treated expression levels are considered to be significant if p ≤ 0.05. To determine the p value two-tailed Student’s t-test was performed, comparing the three individual control amounts with the three corresponding treated samples

From: Effect of IAPP on the proteome of cultured Rin-5F cells

Accession # UniProt Id Description Mean ratio (IAPP treated/control) SD p Value
IPI00194045 Q0QER8/P41562 Isocitrate dehydrogenase NADP cytoplasmic 175 6 0.033
IPI00204532 D3ZYT1 Ubiquitin carboxyl terminal hydrolase 88 3 0.043
IPI00372214 Q4V7C6/D4A7I4 GMP synthase glutamine hydrolyzing 116 0.9 0.035
IPI00421995 Q6MG61 Chloride intracellular channel protein 1 302 1 0.015
IPI00209115 Q6IRH6 Solute carrier family 25 Mitochondrial carrier 87 0.6 0.031