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Fig. 3 | BMC Biochemistry

Fig. 3

From: Kv1.3 contains an alternative C-terminal ER exit motif and is recruited into COPII vesicles by Sec24a

Fig. 3

Retention of Kv1.3-eGFP in the ER upon sequential mutation of the acidic motif. Bar graph depicting the amount of Kv1.3-eGFP or mutant proteins retained in the ER. Ratio of relative percent intensity is equal to the amount of protein retained in the ER microsome fractions divided by the total amount of protein from whole cell homogenates. Resulting values were plotted as the mean ± standard error of the mean of three replicates (n = 3). The only statistically different mutant was the Kv1.3-eGFP E443A-E445A-E447A by one-way ANOVA, Bonferoni correction applied for Type-1 errors (p > 0.008)

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BMC Biochemistry

ISSN: 1471-2091

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