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Figure 1 | BMC Biochemistry

Figure 1

From: A novel bifunctional N-acetylglutamate synthase-kinase from Xanthomonas campestris that is closely related to mammalian N-acetylglutamate synthase

Figure 1

Arginine biosynthesis in microorganisms and plants. Most microbes and plants utilize a "cyclical" pathway in which ornithine acetyltransferase recycles the acetyl group from acetylornithine to glutamate. In these organisms, NAGS replenishes NAG lost in cell division and growth. Some bacteria, such as E. coli and Xanthomonadales, utilize a "linear" pathway in which NAGS catalyzes formation of the first intermediate of arginine biosynthesis. Abbreviations: NAGP, N-acetylglutamyl phosphate; NAGPR, N-acetylglutamyl phosphate reductase; AOAT, acetylornithine aminotransferase; OAT, ornithine acetyltransferase; AOD, acetylornithine deacetylase, OTC, ornithine transcarbamylase, ASS, argininosuccinate synthase; ASL, argininosuccinate lyase.

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