Pattern similarity study of functional sites in protein sequences: lysozymes and cystatins

BMC Biochemistry

Table 1 Determination of active sites in sequences of lysozymes in different families

Family	Active sites	Position	Charge 1	Charge 2	Turn 1	Turn 2
Hen	1	55(35)E	1.0/5.0	.98/5.0	1.0/1.12
	2	81(52)D	.98/5.2	1.0/5.2		1.0/1.21
Hman	1	55(35)E	1.0/5.9	.98/5.0	.98/1.17
	2	81(53)D	.98/5.2	1.0/5.2		1.01/1.22
Goose	1	79(73)E	.67/6.9	.78/6.9	.06/1.03
	2	103(97)D	.83/7.3	.83/7.3		.67/,92
T4	1	11(11)E	.61/4.5	.55/4.5	.76/1.16
	2	20(20)D	.55/5.4	.55/5.4		.53/1.07
CH	1	14(9)D	.98/5.2	1.0/5.2		.95/.95
	2	104(98)D	.74/4.5	.65/4.5		.81/.92
	3	106(100)E	.95/5.6	.86/5.6		.87/.97

Position: the first number is the multiple sequence alignment position shown in Figure 2. Number in bracket is that in the sequence of each lysozyme. Charge 1 and 2 and Turn 1 and 2: Sites 54–57 and 80–83 (alignment position numbers in Fig. 2) were used as references. These position numbers correspond to 34–37 and 50–54, respectively in the sequence of hen lysozyme. The first and second digits n each cell of Charge and Turn are similarity constant and average of property value.

ISSN: 1471-2091