Figure 3From: A strategy using NMR peptide structures of thromboxane A2 receptor as templates to construct ligand-recognition pocket of prostacyclin receptorThe predicted backbone structures of the three eLP domains of the human IP receptor. The 3-D structural models of the eLPs were constructed by homology modeling with the NMR structures of the eLP2 (48), the eLP3 (49) and the eLP1 (unpublished data) of the human TP receptor as templates using the molecular modeling package of Insight II and Discover software packages. The conformation of the eLP2 is placed in a position with respect to the formation of a disulfide bond between the Cys92 in the eLP1 and Cys170 in the eLP2.Back to article page