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Figure 4 | BMC Biochemistry

Figure 4

From: Inhibition of the MEK1/ERK pathway reduces arachidonic acid release independently of cPLA2 phosphorylation and translocation

Figure 4

Effect of U0126 on translocation of EYFP-cPLA 2 following ATP or IONO stimulation Cells expressing EYFP-cPLA2 were incubated with 10 μM U0126 (B, D) or vehicle (A, C) for 15 min prior to stimulation with 100 μM ATP (A, B) or 10 μM IONO (C, D). Representative frames from time-lapse images show the distribution of EYFP-cPLA2 fluorescence before and after stimulation. Results are representative of 4 independent experiments and analysis of several cells per experiment.

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