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Figure 2 | BMC Biochemistry

Figure 2

From: The basic amino acids in the coiled-coil domain of CIN85 regulate its interaction with c-Cbl and phosphatidic acid during epidermal growth factor receptor (EGFR) endocytosis

Figure 2

The net positive charges in group A (K645, K646, R648 and R650) are more important than their positions. (A) The construction of point mutations in group A. (B) Interaction of the mutants with phosphatidic acid. (C) The association of the mutants with intracellular membrane vesicles. (D) Chemical cross-link of CIN85 mutants by dimethylpimelimidate (DMP). The labels in this figure are the same as in Figure 1.

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BMC Biochemistry

ISSN: 1471-2091

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