Figure 7
From: Presenilin-1 regulates the constitutive turnover of the fibronectin matrix in endothelial cells
Levels of fibronectin RNA are not consistently changed in PS1−/− endothelial cells. In panel A, fibronectin RNA was measured in endothelial cell cultures (n=3/genotype per passage) by qPCR for the passages indicated. Samples were run in triplicate and normalized to the geometric means of Ppia, β-actin and Gusb. In panel B, the pooled data for passages 2 and 3 is presented. Statistically significant differences (unpaired t-tests) are indicated above selected comparisons. Statistical comparisons are discussed further in the text.