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Figure 3 | BMC Biochemistry

Figure 3

From: Application of Celluspots peptide arrays for the analysis of the binding specificity of epigenetic reading domains to modified histone tails

Figure 3

Binding of wild type HP1ß and its E23A variant to Celluspots arrays showing similar binding specificity. Highlighted are some of the spots which carry H3K9me2 and H3R8me2s, some of them together with other modifications. The E23A variant binds better to these spots indicating that the negative effect of H3R8me2s on binding of H3K9me2 is reduced by the E23A mutation.

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BMC Biochemistry

ISSN: 1471-2091

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