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Figure 7 | BMC Biochemistry

Figure 7

From: All Dact (Dapper/Frodo) scaffold proteins dimerize and exhibit conserved interactions with Vangl, Dvl, and serine/threonine kinases

Figure 7

All Dacts homo- and hetero-dimerize mediated by their leucine zipper domains. A, Dact1. B, Dact2. C, Dact3. D, Schematic summary of interactions: shading indicates relative strength of coIP; homo-interaction coIPs are modestly more robust than hetero-interaction coIPs. E-G The leucine zipper domain is necessary and sufficient for Dact1 homo-interactions: E, Dependency on the Dact1 N-terminus analyzed using serial N-terminal truncations. F, Dependency on the Dact1 C-terminus analyzed using serial C-terminal truncations. G, Schematic summary of results from E & F.

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BMC Biochemistry

ISSN: 1471-2091

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