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Table 1 Kinetic constants for the inhibition of L1 RT by NRTIs

From: Effect of reverse transcriptase inhibitors on LINE-1 and Ty1 reverse transcriptase activities and on LINE-1 retrotransposition

RT inhibitors

AZTTP

d4TTP

ddCTP

3TCTP

Ki (nM)

16.4 ± 4.21

0.73 ± 0.22

0.72 ± 0.16

12.9 ± 0.16

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BMC Biochemistry

ISSN: 1471-2091

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