Figure 2
![Figure 2](http://media.springernature.com/full/springer-static/image/art%3A10.1186%2F1471-2091-12-15/MediaObjects/12858_2010_Article_324_Fig2_HTML.jpg)
Effects of bergamot extracts on the IL-8 release. IB3-1 cells were treated with 80 ng/ml of TNF-α and increasing amounts (a: IC25; b:IC50; c:IC75) of bergamot extracts. After 24 hours, recovered supernatants were analyzed using the Bio-Plex human cytokine IL-8 single-plex (Bio-Rad). (-): untreated IB3-1 cells; (+): IB3-1 cells treated with TNF-α. Results represent the average ± S.D. of three independent experiments. For each experiment duplicate determinations were performed. (*) p < 0.05.