Genetic environment of the mak gene in different organisms. Organization of the region containing the mak gene in Mycobacterium bovis BCG, M. tuberculosis, M. marinum, M. leprae, Actinoplanes missouriensis, Rubrobacter xylanophilus, Chloroflexus sp. and Pseudomonas entomophila. Arrows represent genes and their orientation. pepA, serine protease; treS, trehalose synthase; mak, maltokinase; glgB, glycogen branching enzyme; fused treS/mak, probable fused trehalose synthase/maltokinase.