Protein and enzyme biochemistry

Section edited by Joel Weiner

Protein and enzyme biochemistry: This section incorporates all aspects of protein and enzyme biochemistry including but not limited to: protein chemistry and proteomics, protein folding and enzyme activity. Applications of these areas, such as in bionanotechnology and biosensors are also welcome.

Previous Page Page 1 of 4 Next Page
  1. Research article

    Structural insight into the inactivation of Mycobacterium tuberculosis non-classical transpeptidase LdtMt2 by biapenem and tebipenem

    The carbapenem subclass of β-lactams is among the most potent antibiotics available today. Emerging evidence shows that, unlike other subclasses of β-lactams, carbapenems bind to and inhibit non-classical tran...

    Mario A. Bianchet, Ying H. Pan, Leighanne A. Brammer Basta, Harry Saavedra, Evan P. Lloyd, Pankaj Kumar, Rohini Mattoo, Craig A. Townsend and Gyanu Lamichhane

    BMC Biochemistry 2017 18:8

    Published on: 25 May 2017

  2. Research article

    Structural similarities and functional differences clarify evolutionary relationships between tRNA healing enzymes and the myelin enzyme CNPase

    Eukaryotic tRNA splicing is an essential process in the transformation of a primary tRNA transcript into a mature functional tRNA molecule. 5′-phosphate ligation involves two steps: a healing reaction catalyze...

    Gopinath Muruganandam, Arne Raasakka, Matti Myllykoski, Inari Kursula and Petri Kursula

    BMC Biochemistry 2017 18:7

    Published on: 16 May 2017

  3. Research article

    Binding of smoothelin-like 1 to tropomyosin and calmodulin is mutually exclusive and regulated by phosphorylation

    The smoothelin-like 1 protein (SMTNL1) can associate with tropomyosin (Tpm) and calmodulin (CaM), two proteins essential to the smooth muscle contractile process. SMTNL1 is phosphorylated at Ser301 by protein ...

    Annegret Ulke-Lemée, David Hao Sun, Hiroaki Ishida, Hans J. Vogel and Justin A. MacDonald

    BMC Biochemistry 2017 18:5

    Published on: 21 March 2017

  4. Research article

    Increased enzymatic hydrolysis of sugarcane bagasse by a novel glucose- and xylose-stimulated β-glucosidase from Anoxybacillus flavithermus subsp. yunnanensis E13T

    β-Glucosidase is claimed as a key enzyme in cellulose hydrolysis. The cellulosic fibers are usually entrapped with hemicelluloses containing xylose. So there is ongoing interest in searching for glucose- and x...

    Yang Liu, Rui Li, Jing Wang, Xiaohan Zhang, Rong Jia, Yi Gao and Hui Peng

    BMC Biochemistry 2017 18:4

    Published on: 16 March 2017

  5. Research article

    Interactions of histatin-3 and histatin-5 with actin

    Histatins are histidine rich polypeptides produced in the parotid and submandibular gland and secreted into the saliva. Histatin-3 and −5 are the most important polycationic histatins. They possess antimicrobi...

    Edna Blotnick, Asaf Sol, Gilad Bachrach and Andras Muhlrad

    BMC Biochemistry 2017 18:3

    Published on: 6 March 2017

  6. Research article

    Identification of replication-dependent and replication-independent linker histone complexes: Tpr specifically promotes replication-dependent linker histone stability

    There are 11 variants of linker histone H1 in mammalian cells. Beyond their shared abilities to stabilize and condense chromatin, the H1 variants have been found to have non-redundant functions, the mechanisms...

    Pei Zhang, Owen E. Branson, Michael A. Freitas and Mark R. Parthun

    BMC Biochemistry 2016 17:18

    Published on: 1 October 2016

  7. Research article

    Effect of mutations to amino acid A301 and F361 in thermostability and catalytic activity of the β-galactosidase from Bacillus subtilis VTCC-DVN-12-01

    Beta-galactosidase (EC 3.2.1.23), a commercially important enzyme, catalyses the hydrolysis of β-1,3- and β-1,4-galactosyl bonds of polymer or oligosaccharidesas well as transglycosylation of β-galactopyranosi...

    Thao Thi Nguyen, Hanh Van Vu, Nhung Thi Hong Nguyen, Tuyen Thi Do and Thanh Sy Le Nguyen

    BMC Biochemistry 2016 17:15

    Published on: 8 July 2016

  8. Research article

    Auto-thiophosphorylation activity of Src tyrosine kinase

    Intermolecular autophosphorylation at Tyr416 is a conserved mechanism of activation among the members of the Src family of nonreceptor tyrosine kinases. Like several other tyrosine kinases, Src can catalyze th...

    M. Zulema Cabail, Emily I. Chen, Antonius Koller and W. Todd Miller

    BMC Biochemistry 2016 17:13

    Published on: 7 July 2016

  9. Research article

    Molecular characterization of protein kinase C delta (PKCδ)-Smac interactions

    Protein kinase C δ (PKCδ) is known to be an important regulator of apoptosis, having mainly pro- but also anti-apoptotic effects depending on context. In a previous study, we found that PKCδ interacts with the...

    Christian Holmgren, Louise Cornmark, Gry Kalstad Lønne, Katarzyna Chmielarska Masoumi and Christer Larsson

    BMC Biochemistry 2016 17:11

    Published on: 23 May 2016

  10. Research article

    1,2-Dichlorobenzene affects the formation of the phosphoenzyme stage during the catalytic cycle of the Ca2+-ATPase from sarcoplasmic reticulum

    1,2-Dichlorobenzene (1,2-DCB) is a benzene-derived molecule with two Cl atoms that is commonly utilized in the synthesis of pesticides. 1,2-DCB can be absorbed by living creatures and its effects on naturally-...

    Javier Vargas-Medrano, Jorge A. Sierra-Fonseca and Luis F. Plenge-Tellechea

    BMC Biochemistry 2016 17:5

    Published on: 11 March 2016

  11. Research article

    Characterization of a cold-active and salt tolerant esterase identified by functional screening of Arctic metagenomic libraries

    The use of metagenomics in enzyme discovery constitutes a powerful approach to access to genomes of unculturable community of microorganisms and isolate novel valuable biocatalysts for use in a wide range of b...

    Concetta De Santi, Bjørn Altermark, Marcin Miroslaw Pierechod, Luca Ambrosino, Donatella de Pascale and Nils-Peder Willassen

    BMC Biochemistry 2016 17:1

    Published on: 19 January 2016

  12. Research article

    A comparison of the enzymatic properties of three recombinant isoforms of thrombolytic and antibacterial protein—Destabilase-Lysozyme from medicinal leech

    Destabilase-Lysozyme (mlDL) is a multifunctional i-type enzyme that has been found in the secretions from the salivary glands of medicinal leeches. mlDL has been shown to exhibit isopeptidase, muramidase and a...

    Alexey S. Kurdyumov, Valentin A. Manuvera, Isolda P. Baskova and Vassili N. Lazarev

    BMC Biochemistry 2015 16:27

    Published on: 21 November 2015

Previous Page Page 1 of 4 Next Page

Can't find what you are looking for?

Articles for this section are still being added to this new-look site. In the meantime you can still view this section on our old site.