Association of TM6SF2 rs58542926 gene polymorphism with the risk of non-alcoholic fatty liver disease and colorectal adenoma in Chinese Han population

Table 6 Clinical characteristics of TM6SF2 rs58542926 T carriers and non-carriers in overall subjects^a

Characteristic	CC (n = 794)	CT + TT (n = 45)	P Value
Age (yr)	54.60 ± 0.49	54.70 ± 0.48	0.863
BMI (kg/m²)	24.26 ± 1.40	24.33 ± 1.41	0.841
CAP (dB/m)	226.68 ± 28.88	243.42 ± 30.14	0.034
FPG (mmol/L)	4.97 ± 0.58	5.03 ± 0.81	0.741
TC (mmol/L)	5.63 ± 0.72	5.09 ± 0.85	0.175
TG (mmol/L)	1.93 ± 1.15	1.53 ± 1.22	0.029
LDL-C (mmol/L)	3.32 ± 0.60	3.16 ± 0.68	0.492
HDL-C (mmol/L)	1.31 ± 0.41	1.43 ± 0.42	0.429
AST (U/L)	39.66 ± 8.50	43.93 ± 7.90	0.042
ALT (U/L)	34.82 ± 10.50	36.57 ± 9.30	0.093
UA (μmol/L)	368.03 ± 74.49	357.46 ± 75.37	0.735

Abbreviations: NAFLD non-alcoholic fatty liver disease, CRA colorectal adenoma, BMI body mass index, CAP controlled attenuation parameter, FPG fasting plasma glucose, TC total cholesterol, TG triglyceride, LDL-C low-density lipoprotein cholesterol, HDL-C high-density lipoprotein cholesterol, AST aspartate aminotransferase, ALT alanine aminotransferase, UA uric acid
^aValues are expressed as mean ± SD and compared by Student’s t-test

ISSN: 1471-2091