Effect of IAPP on the proteome of cultured Rin-5F cells

Miraee-Nedjad, Samaneh; Sims, Paul F. G.; Schwartz, Jean-Marc; Doig, Andrew J.

doi:10.1186/s12858-018-0099-3

BMC Biochemistry

Table 6 Twenty Top Proteins for Protein-Protein Interaction Network Parameter Terms (network degree, closeness centrality and betweenness centrality). Proteins with a closeness centrality of 1.0 were excluded as they correspond to isolated protein pairs

From: Effect of IAPP on the proteome of cultured Rin-5F cells

Protein	Accession #	Degree	Fold change	Protein	Accession #	Closeness centrality	Fold change	Protein	Accession #	Between-ness centrality	Fold change
Tpi1	IPI00231767	47	1.8	Gapdh	IPI00555252	0.481	0.34	Gapdh	IPI00555252	0.135	0.34
Mdh2	IPI00197696	38	0.29	Tpi1	IPI00231767	0.463	1.5	Pcna	IPI00200861	0.127	0.89
Sod2	IPI00211593	38	1.1	Alb	IPI00191737	0.460	1.3	Actb	IPI00189819	0.0683	0.94
Gapdh	IPI00555252	37	0.34	Pcna	IPI00200861	0.444	0.88	Alb	IPI00191737	0.0645	1.3
Cs	IPI00206977	35	1.1	Atp5a1	IPI00396910	0.441	1.1	Eef2	IPI00203214	0.0574	1.1
Atp5a1	IPI00396910	34	1.1	Atp5b	IPI00551812	0.440	0.44	Atp5a1	IPI00396910	0.0522	1.1
Atp5b	IPI00551812	33	0.44	Pgk1	IPI00231426	0.438	0.92	Tpi1	IPI00231767	0.0506	1.5
Pkm2	IPI00231929	31	0.59	Eef2	IPI00203214	0.436	1.1	Cfl1	IPI00327144	0.0387	1.4
Shmt2	IPI00195109	30	1.2	Shmt2	IPI00195109	0.436	1.2	Glud1	IPI00324633	0.0383	2.1
Glud1	IPI00324633	30	2.1	Cs	IPI00206977	0.435	1.1	Gnb2l1	IPI00231134	0.0372	1.5
Dld	IPI00365545	30	1.9	Pkm2	IPI00231929	0.431	0.59	Gmps	IPI00372214	0.0371	120
Alb	IPI00191737	29	1.3	Dhfr	IPI00200419	0.429	1.2	Rad23b	IPI00210495	0.0359	0.96
Pgk1	IPI00231426	27	0.92	Mdh2	IPI00197696	0.424	0.29	Stip1	IPI00213013	0.0343	2.0
Pcna	IPI00200861	25	0.88	Actb	IPI00189819	0.423	0.94	Mdh2	IPI00197696	0.0332	0.29
Gmps	IPI00372214	25	120	Hspa4	IPI00387868	0.423	0.27	Tubb5	IPI00197579	0.0317	0.15
Eef2	IPI00203214	24	1.1	Sod2	IPI00211593	0.422	1.1	Shmt2	IPI00195109	0.0303	1.2
Mdh1	IPI00198717	24	6.0	Gmps	IPI00372214	0.419	120	Eif5a	IPI00211216	0.0286	0.34
Gnb2l1	IPI00231134	23	1.5	Gnb2\|1	IPI00231134	0.413	1.5	Dars	IPI00206224	0.0257	1.1
Sod1	IPI00231643	23	0.52	Txn1	IPI00216298	0.411	29	Aprt	IPI00950965	0.0256	0.016
Txn1	IPI00231368	23	29	Sod1	IPI00231643	0.409	0.52	Ywhaz	IPI00324893	0.0250	0.56

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ISSN: 1471-2091

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