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Table 5 Pathways Identified for Down-Regulated Proteins

From: Effect of IAPP on the proteome of cultured Rin-5F cells

Protein ID Protein Name Pathway
P54921 NSF attachment protein alpha(Napa) Synaptic vesicle cycle
B5DEH4 UDP-N-acetylglucosamine pyrophosphorylase 1 like 1(Uap1l1) Amino sugar and nucleotide sugar metabolism, Metabolic pathways, Biosynthesis of antibiotics
B2GV73 actin related protein 2/3 complex, subunit 3(Arpc3) Endocytosis, Fc gamma R-mediated phagocytosis, Regulation of actin cytoskeleton, Bacterial invasion of epithelial cells, Salmonella infection.
P07335 creatine kinase B(Ckb) Arginine and proline metabolism, Metabolic pathways
Q68FR9 eukaryotic translation elongation factor 1 delta(Eef1d) Herpes simplex infection
O88600, F1LRV4 heat shock protein family A member 4(Hspa4) Antigen processing and presentation
P04636, Q0QF43 malate dehydrogenase 2(Mdh2) Citrate cycle (TCA cycle), Cysteine and methionine metabolism, Pyruvate metabolism, Glyoxylate and dicarboxylate metabolism, Metabolic pathways, Biosynthesis of antibiotics, Carbon metabolism
Q63716 peroxiredoxin 1(Prdx1) Peroxisome
P04961 proliferating cell nuclear antigen(Pcna) DNA replication, Base excision repair, Nucleotide excision repair, Mismatch repair, Cell cycle, Hepatitis B, HTLV-I infection
B2GV92, P83868 prostaglandin E synthase 3(Ptges3) Arachidonic acid metabolism, Metabolic pathways
Q4FZT9 proteasome 26S subunit, non-ATPase 2(Psmd2) Proteasome, Epstein-Barr virus infection
Q5XI34 protein phosphatase 2 scaffold subunit A alpha(Ppp2r1a) mRNA surveillance pathway, Sphingolipid signalling pathway, Oocyte meiosis, PI3K-Akt signalling pathway, AMPK signalling pathway, Adrenergic signalling in cardiomyocytes, TGF-beta signalling pathway, Hippo signalling pathway, Tight junction, Dopaminergic synapse, Long-term depression, Chagas disease (American trypanosomiasis), Hepatitis C
P19945 ribosomal protein lateral stalk subunit P0(Rplp0) Ribosome
P18297, B2RYK3 sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase)(Spr) Folate biosynthesis, Metabolic pathways
Q9EQS0 transaldolase 1(Taldo1) Pentose phosphate pathway, Metabolic pathways, Biosynthesis of antibiotics, Carbon metabolism, Biosynthesis of amino acids
P63102 tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta(Ywhaz) Cell cycle, Oocyte meiosis, PI3K-Akt signalling pathway, Hippo signalling pathway, Hepatitis B, Epstein-Barr virus infection, Viral carcinogenesis
Q9EQX9 ubiquitin-conjugating enzyme E2N(Ube2n) Ubiquitin mediated proteolysis