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Table 5 Pathways Identified for Down-Regulated Proteins

From: Effect of IAPP on the proteome of cultured Rin-5F cells

Protein ID

Protein Name

Pathway

P54921

NSF attachment protein alpha(Napa)

Synaptic vesicle cycle

B5DEH4

UDP-N-acetylglucosamine pyrophosphorylase 1 like 1(Uap1l1)

Amino sugar and nucleotide sugar metabolism, Metabolic pathways, Biosynthesis of antibiotics

B2GV73

actin related protein 2/3 complex, subunit 3(Arpc3)

Endocytosis, Fc gamma R-mediated phagocytosis, Regulation of actin cytoskeleton, Bacterial invasion of epithelial cells, Salmonella infection.

P07335

creatine kinase B(Ckb)

Arginine and proline metabolism, Metabolic pathways

Q68FR9

eukaryotic translation elongation factor 1 delta(Eef1d)

Herpes simplex infection

O88600, F1LRV4

heat shock protein family A member 4(Hspa4)

Antigen processing and presentation

P04636, Q0QF43

malate dehydrogenase 2(Mdh2)

Citrate cycle (TCA cycle), Cysteine and methionine metabolism, Pyruvate metabolism, Glyoxylate and dicarboxylate metabolism, Metabolic pathways, Biosynthesis of antibiotics, Carbon metabolism

Q63716

peroxiredoxin 1(Prdx1)

Peroxisome

P04961

proliferating cell nuclear antigen(Pcna)

DNA replication, Base excision repair, Nucleotide excision repair, Mismatch repair, Cell cycle, Hepatitis B, HTLV-I infection

B2GV92, P83868

prostaglandin E synthase 3(Ptges3)

Arachidonic acid metabolism, Metabolic pathways

Q4FZT9

proteasome 26S subunit, non-ATPase 2(Psmd2)

Proteasome, Epstein-Barr virus infection

Q5XI34

protein phosphatase 2 scaffold subunit A alpha(Ppp2r1a)

mRNA surveillance pathway, Sphingolipid signalling pathway, Oocyte meiosis, PI3K-Akt signalling pathway, AMPK signalling pathway, Adrenergic signalling in cardiomyocytes, TGF-beta signalling pathway, Hippo signalling pathway, Tight junction, Dopaminergic synapse, Long-term depression, Chagas disease (American trypanosomiasis), Hepatitis C

P19945

ribosomal protein lateral stalk subunit P0(Rplp0)

Ribosome

P18297, B2RYK3

sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase)(Spr)

Folate biosynthesis, Metabolic pathways

Q9EQS0

transaldolase 1(Taldo1)

Pentose phosphate pathway, Metabolic pathways, Biosynthesis of antibiotics, Carbon metabolism, Biosynthesis of amino acids

P63102

tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta(Ywhaz)

Cell cycle, Oocyte meiosis, PI3K-Akt signalling pathway, Hippo signalling pathway, Hepatitis B, Epstein-Barr virus infection, Viral carcinogenesis

Q9EQX9

ubiquitin-conjugating enzyme E2N(Ube2n)

Ubiquitin mediated proteolysis