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Fig. 7 | BMC Biochemistry

Fig. 7

From: Serendipitous discovery of light-induced (In Situ) formation of an Azo-bridged dimeric sulfonated naphthol as a potent PTP1B inhibitor

Fig. 7

Global non-linear regression fit for competitive inhibition of DUSP5 PD(WT) with RR601. DUSP5 PD(WT) reaction velocities were measured in assay buffer containing 1, 3, 9, 27 and 81 mM pNPP in the presence of 0, 3, 10, 30 and 75 μM RR601. The data was fit with GraphPad curve fitting software. Best fit estimates (± SE) for Vmax, Km and Ki are 0.70 ± 0.02 μM · min-1, 9.6 ± 0.9 mM and 18.8 ± 2.5 μM, respectively

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BMC Biochemistry

ISSN: 1471-2091

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