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Table 2 UPLC-HRMS of Inhibited LdMt2 species

From: Structural insight into the inactivation of Mycobacterium tuberculosis non-classical transpeptidase LdtMt2 by biapenem and tebipenem

m/z (Da)

Species

Intensity from the maximum %

 (56-408)LdtMt2 (exact mass Mn = 38085.5 Da)

38085.5

[Mn + H]+

100%

 biapenem (exact mass = 352.1 Da)

38225.0

[Mn + 139.5 + H]+

100%

 tebipenem (exact mass = 384.1 Da)

38469.6

[Mn + 384 + H]+

44%

38425.0

[Mn + 339 + H]+

39%

38117.0

[Mn + 32 + H]+

13%

  1. M/z for native LdtMt2 and its species inactivated by biapenem and tebipenem. The exact mass for apo-LdtMt2 was calculated using ExPASy MW server. See also in Additional file 1: Figure S2 for the mass spectra
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BMC Biochemistry

ISSN: 1471-2091

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