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Table 1 Constituents of the pathway profiling database. The types of cellular signals for the reporter gene assays and cell lines of the proliferation assays are shown

From: Tubulin is a molecular target of the Wnt-activating chemical probe

Cellular reporter gene assays Cellular proliferation assays
cAMP response element (CRE) signal HEK293T
Nuclear factor of activated T-cells (NFAT) signal MRC5 (high density)
Nuclear factor kappa- light-chain-enhancer of activated B cells (NF-kB) signal MRC5 (low density)
Serum response element (SRE) signal A549
Serum response factor (SRF) signal PC3
p53 signal LNCaP
E2F signal Jurkat
Activating transcription factor 6 signal MDA-MB-231
Hedgehog signal  
Hypoxia-inducible factor 1 (HIF1) signal  
Nuclear factor erythroid 2-related factor 2 (Nrf2) signal  
SMAD signal  
Wnt signal