Fig. 6
From: Conserved motif VIII of murine DNA methyltransferase Dnmt3a is essential for methylation activity

Analysis of covalent complex formation of Dnmt3a-CD wt and its variants with 2-pyrimidinone-substituted DNA duplex fC G/G P. Fluorograph of a 12.5 % denaturing Laemmli polyacrylamide gel. The samples were treated with 1 % SDS for 10 min at room temperature