Fig. 5
From: Conserved motif VIII of murine DNA methyltransferase Dnmt3a is essential for methylation activity
Base flipping induced by Dnmt3a-CD or its variants in complex with Dnmt3L. Emission spectra were recorded for the complex of Dnmt3a-CD (300 nM) with Dnmt3L (300 nM) and 2-aminopurine containing hemimethylated DNA duplex GB GC/CGMG (200 nM) in the presence of AdoMet (0.1 mM)