Figure 3
From: Sigma-1 receptor directly interacts with Rac1-GTPase in the brain mitochondria
Effects of pentazocine and haloperidol on the NADPH oxidase activity. Mitochondria were incubated with haloperidol (H), with (+)-pentazocine (P) or with both ligands (H + P) and NADPH oxidase activity determined as described in Material and methods. Data represented are mean ± SEM of results from four separate experiments performed in duplicate. *P < 0.05, t test compared with corresponding control (C).