Table 1 Initial rate of 14C MV2+ transported by EmrE and TBsmr as a function of lipid composition
From: Lipid bilayer composition influences small multidrug transporters
| Â | EmrE Initial rate of 14C MV2+ transport (nmol. min-1. mg-1) | TBsmr Initial rate of 14C MV2+ transport (nmol. min-1. mg-1) | ||||||
|---|---|---|---|---|---|---|---|---|
Mole fraction of added lipida | DOPC/DOPE (PE added to PC) | DOPC/DOPG (PG added to PC) | DOPG/DOPE (PE added to PG) | DOPC/DOPE (PE added to PC) | DOPC/DOPG (PG added to PC) | DOPG/DOPE (PE added to PG) | DOPC/SoyPI (PI added to PG) | SoyPI/DOPE (PE added to PI) |
0 | 14 | 14 | 81 | 13 | 13 | 58 | 13 | 53 |
0.1 | 32 | 7 | 135 | 7 | 7 | 23 | 45 | ND |
0.2 | 62 | 67 | 95 | 7 | 22 | 49 | 50 | 86 |
0.3 | 213 | 18 | 149 | 12 | 18 | 26 | 43 | ND |
0.4 | 349 | 291 | 138 | 55 | 30 | 26 | 261 | 316 |
0.5 | 235 | 286 | 301 | 44 | 30 | 29 | 251 | ND |
0.6 | 76 | 292 | 409 | 22 | 59 | 47 | 104 | 331 |
0.7 | 179 | 315 | 577 | 33 | 28 | 39 | 94 | ND |