Figure 9
From: YB-1 promotes microtubule assembly in vitro through interaction with tubulin and microtubules
YB-1 induces the formation of single wall microtubules. Tubulin (30 μM) was polymerized without (A, C, C') or with 10 μM YB-1 (B, D, D') at 37°C. Transmission electron microscopy of longitudinal ultrathin sections revealed that YB-1 contributes to the formation of normal microtubules and that, in addition, the microtubules remain regularly spaced from one another (compare B with the control A). Transversal sections of microtubules (C, D) confirmed this observation. B, C, D are at the same magnification as A. D' is at the same magnification as C'.