Figure 1
The Swiss-Model 3D-structure of V. carchariae chitinase A. A ribbon representation of the 3D-structure of V. carchariae chitinase A was constructed based on the x-ray structure of S. marcescens Chi A E315L mutant as described in the text. The N-terminal chitin binding domain is presented in cyan, the TIM barrel domain in yellow and the small insertion domain in green. The coordinates of [GlcNAc]6 that are modeled in the active site of the Vibrio enzyme are shown as a stick model with N atoms in blue and O atoms in red. The mutated residues (Ser33, Trp70, Trp231 and Tyr245) and other substrate binding residues are also presented in stick model (magenta).