TY - JOUR AU - Ciechanover, A. AU - Brundin, P. PY - 2003 DA - 2003// TI - The ubiquitin proteasome system in neurodegenerative diseases: sometimes the chicken, sometimes the egg JO - Neuron VL - 40 UR - https://doi.org/10.1016/S0896-6273(03)00606-8 DO - 10.1016/S0896-6273(03)00606-8 ID - Ciechanover2003 ER - TY - JOUR AU - Hegde, A. N. PY - 2004 DA - 2004// TI - Ubiquitin-proteasome-mediated local protein degradation and synaptic plasticity JO - Prog Neurobiol VL - 73 UR - https://doi.org/10.1016/j.pneurobio.2004.05.005 DO - 10.1016/j.pneurobio.2004.05.005 ID - Hegde2004 ER - TY - JOUR AU - Bartus, R. T. AU - Dean, R. L. AU - Beer, B. AU - Lippa, A. S. PY - 1982 DA - 1982// TI - The cholinergic hypothesis of geriatric memory dysfunction JO - Science VL - 217 UR - https://doi.org/10.1126/science.7046051 DO - 10.1126/science.7046051 ID - Bartus1982 ER - TY - JOUR AU - Graeber, M. B. AU - Kosel, S. AU - Egensperger, R. AU - Banati, R. B. AU - Muller, U. AU - Bise, K. PY - 1997 DA - 1997// TI - Rediscovery of the case described by Alois Alzheimer in 1911: historical, histological and molecular genetic analysis JO - Neurogenetics VL - 1 UR - https://doi.org/10.1007/s100480050011 DO - 10.1007/s100480050011 ID - Graeber1997 ER - TY - JOUR AU - Mattson, M. P. PY - 2004 DA - 2004// TI - Pathways towards and away from Alzheimer's disease JO - Nature VL - 430 UR - https://doi.org/10.1038/nature02621 DO - 10.1038/nature02621 ID - Mattson2004 ER - TY - JOUR AU - Moller, H. J. AU - Graeber, M. B. PY - 1998 DA - 1998// TI - The case described by Alois Alzheimer in Historical and conceptual perspectives based on the clinical record and neurohistological sections JO - Eur Arch Psychiatry Clin Neurosci VL - 248 UR - https://doi.org/10.1007/s004060050027 DO - 10.1007/s004060050027 ID - Moller1998 ER - TY - JOUR AU - Perry, G. AU - Rizzuto, N. AU - utilio-Gambetti, L. AU - Gambetti, P. PY - 1985 DA - 1985// TI - Paired helical filaments from Alzheimer disease patients contain cytoskeletal components JO - Proc Natl Acad Sci U S A VL - 82 UR - https://doi.org/10.1073/pnas.82.11.3916 DO - 10.1073/pnas.82.11.3916 ID - Perry1985 ER - TY - JOUR AU - Selkoe, D. J. PY - 1991 DA - 1991// TI - The molecular pathology of Alzheimer's disease JO - Neuron VL - 6 UR - https://doi.org/10.1016/0896-6273(91)90052-2 DO - 10.1016/0896-6273(91)90052-2 ID - Selkoe1991 ER - TY - JOUR AU - Blennow, K. AU - de Leon, M. J. AU - Zetterberg, H. PY - 2006 DA - 2006// TI - Alzheimer's disease JO - Lancet VL - 368 UR - https://doi.org/10.1016/S0140-6736(06)69113-7 DO - 10.1016/S0140-6736(06)69113-7 ID - Blennow2006 ER - TY - JOUR AU - Iwata, N. AU - Higuchi, M. AU - Saido, T. PY - 2005 DA - 2005// TI - Metabolism of amyloid-beta peptide and Alzheimer's disease JO - Pharmacology & Therapeutics VL - 108 UR - https://doi.org/10.1016/j.pharmthera.2005.03.010 DO - 10.1016/j.pharmthera.2005.03.010 ID - Iwata2005 ER - TY - JOUR AU - Masters, C. L. AU - Simms, G. AU - Weinman, N. A. AU - Multhaup, G. AU - McDonald, B. L. AU - Beyreuther, K. PY - 1985 DA - 1985// TI - Amyloid plaque core protein in Alzheimer disease and Down syndrome JO - Proc Natl Acad Sci U S A VL - 82 UR - https://doi.org/10.1073/pnas.82.12.4245 DO - 10.1073/pnas.82.12.4245 ID - Masters1985 ER - TY - JOUR AU - Selkoe, D. J. PY - 2001 DA - 2001// TI - Alzheimer's disease: genes, proteins, and therapy JO - Physiol Rev VL - 81 ID - Selkoe2001 ER - TY - JOUR AU - Hardy, J. AU - Selkoe, D. PY - 2002 DA - 2002// TI - The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics JO - Science VL - 297 UR - https://doi.org/10.1126/science.1072994 DO - 10.1126/science.1072994 ID - Hardy2002 ER - TY - JOUR AU - Selkoe, D. PY - 2002 DA - 2002// TI - Alzheimer's disease is a synaptic failure JO - Science VL - 298 UR - https://doi.org/10.1126/science.1074069 DO - 10.1126/science.1074069 ID - Selkoe2002 ER - TY - JOUR AU - Terry, R. D. AU - Masliah, E. AU - Salmon, D. P. AU - Butters, N. AU - DeTeresa, R. AU - Hill, R. PY - 1991 DA - 1991// TI - Physical basis of cognitive alterations in Alzheimer's disease: synapse loss is the major correlate of cognitive impairment JO - Ann Neurol VL - 30 UR - https://doi.org/10.1002/ana.410300410 DO - 10.1002/ana.410300410 ID - Terry1991 ER - TY - JOUR AU - Hsia, A. Y. AU - Masliah, E. AU - McConlogue, L. AU - Yu, G. Q. AU - Tatsuno, G. AU - Hu, K. PY - 1999 DA - 1999// TI - Plaque-independent disruption of neural circuits in Alzheimer's disease mouse models JO - Proc Natl Acad Sci U S A VL - 96 UR - https://doi.org/10.1073/pnas.96.6.3228 DO - 10.1073/pnas.96.6.3228 ID - Hsia1999 ER - TY - JOUR AU - Mucke, L. AU - Masliah, E. AU - Yu, G. Q. AU - Mallory, M. AU - Rockenstein, E. M. AU - Tatsuno, G. PY - 2000 DA - 2000// TI - High-level neuronal expression of abeta 1-42 in wild-type human amyloid protein precursor transgenic mice: synaptotoxicity without plaque formation JO - J Neurosci VL - 20 ID - Mucke2000 ER - TY - JOUR AU - Larson, J. AU - Lynch, G. AU - Games, D. AU - Seubert, P. PY - 1999 DA - 1999// TI - Alterations in synaptic transmission and long-term potentiation in hippocampal slices from young and aged PDAPP mice JO - Brain Research VL - 840 UR - https://doi.org/10.1016/S0006-8993(99)01698-4 DO - 10.1016/S0006-8993(99)01698-4 ID - Larson1999 ER - TY - JOUR AU - Moechars, D. AU - Dewachter, I. AU - Lorent, K. AU - Reverse, D. AU - Baekelandt, V. AU - Naidu, A. PY - 1999 DA - 1999// TI - Early phenotypic changes in transgenic mice that overexpress different mutants of amyloid precursor protein in brain JO - Journal of Biological Chemistry VL - 274 UR - https://doi.org/10.1074/jbc.274.10.6483 DO - 10.1074/jbc.274.10.6483 ID - Moechars1999 ER - TY - JOUR AU - Vitolo, O. V. AU - Sant'Angelo, A. AU - Costanzo, V. AU - Battaglia, F. AU - Arancio, O. AU - Shelanski, M. PY - 2002 DA - 2002// TI - Amyloid beta -peptide inhibition of the PKA/CREB pathway and long-term potentiation: reversibility by drugs that enhance cAMP signaling JO - Proc Natl Acad Sci U S A VL - 99 UR - https://doi.org/10.1073/pnas.172504199 DO - 10.1073/pnas.172504199 ID - Vitolo2002 ER - TY - JOUR AU - Hsiao, K. AU - Chapman, P. AU - Nilsen, S. AU - Eckman, C. AU - Harigaya, Y. AU - Younkin, S. PY - 1996 DA - 1996// TI - Correlative memory deficits, Abeta elevation, and amyloid plaques in transgenic mice JO - Science VL - 274 UR - https://doi.org/10.1126/science.274.5284.99 DO - 10.1126/science.274.5284.99 ID - Hsiao1996 ER - TY - JOUR AU - Chapman, P. F. AU - White, G. L. AU - Jones, M. W. AU - Cooper-Blacketer, D. AU - Marshall, V. J. AU - Irizarry, M. PY - 1999 DA - 1999// TI - Impaired synaptic plasticity and learning in aged amyloid precursor protein transgenic mice JO - Nature Neuroscience VL - 2 UR - https://doi.org/10.1038/6374 DO - 10.1038/6374 ID - Chapman1999 ER - TY - JOUR AU - Walsh, D. M. AU - Klyubin, I. AU - Fadeeva, J. V. AU - Cullen, W. K. AU - Anwyl, R. AU - Wolfe, M. S. PY - 2002 DA - 2002// TI - Naturally secreted oligomers of amyloid beta protein potently inhibit hippocampal long-term potentiation in vivo JO - Nature VL - 416 UR - https://doi.org/10.1038/416535a DO - 10.1038/416535a ID - Walsh2002 ER - TY - JOUR AU - Forman, M. S. AU - Farmer, J. AU - Johnson, J. K. AU - Clark, C. M. AU - Arnold, S. E. AU - Coslett, H. B. PY - 2006 DA - 2006// TI - Frontotemporal dementia: clinicopathological correlations JO - Ann Neurol VL - 59 UR - https://doi.org/10.1002/ana.20873 DO - 10.1002/ana.20873 ID - Forman2006 ER - TY - JOUR AU - Layfield, R. AU - Lowe, J. AU - Bedford, L. PY - 2005 DA - 2005// TI - The ubiquitin-proteasome system and neurodegenerative disorders JO - Essays Biochem VL - 41 UR - https://doi.org/10.1042/bse0410157 DO - 10.1042/bse0410157 ID - Layfield2005 ER - TY - JOUR AU - Lowe, J. AU - Blanchard, A. AU - Morrell, K. AU - Lennox, G. AU - Reynolds, L. AU - Billett, M. PY - 1988 DA - 1988// TI - Ubiquitin is a common factor in intermediate filament inclusion bodies of diverse type in man, including those of Parkinson's disease, Pick's disease, and Alzheimer's disease, as well as Rosenthal fibres in cerebellar astrocytomas, cytoplasmic bodies in muscle, and mallory bodies in alcoholic liver disease JO - J Pathol VL - 155 UR - https://doi.org/10.1002/path.1711550105 DO - 10.1002/path.1711550105 ID - Lowe1988 ER - TY - JOUR AU - Mayer, R. J. AU - Tipler, C. AU - Arnold, J. AU - Laszlo, L. AU - Al-Khedhairy, A. AU - Lowe, J. PY - 1996 DA - 1996// TI - Endosome-lysosomes, ubiquitin and neurodegeneration JO - Adv Exp Med Biol VL - 389 UR - https://doi.org/10.1007/978-1-4613-0335-0_33 DO - 10.1007/978-1-4613-0335-0_33 ID - Mayer1996 ER - TY - JOUR AU - Mori, H. AU - Kondo, J. AU - Ihara, Y. PY - 1987 DA - 1987// TI - Ubiquitin is a component of paired helical filaments in Alzheimer's disease JO - Science VL - 235 UR - https://doi.org/10.1126/science.3029875 DO - 10.1126/science.3029875 ID - Mori1987 ER - TY - JOUR AU - Perry, G. AU - Friedman, R. AU - Shaw, G. AU - Chau, V. PY - 1987 DA - 1987// TI - Ubiquitin is detected in neurofibrillary tangles and senile plaque neurites of Alzheimer disease brains JO - Proc Natl Acad Sci U S A VL - 84 UR - https://doi.org/10.1073/pnas.84.9.3033 DO - 10.1073/pnas.84.9.3033 ID - Perry1987 ER - TY - JOUR AU - Braak, H. AU - Braak, E. PY - 1991 DA - 1991// TI - Neuropathological stageing of Alzheimer-related changes JO - Acta Neuropathol (Berl) VL - 82 UR - https://doi.org/10.1007/BF00308809 DO - 10.1007/BF00308809 ID - Braak1991 ER - TY - JOUR AU - Johnston, J. A. AU - Ward, C. L. AU - Kopito, R. PY - 1998 DA - 1998// TI - Aggresomes: a cellular response to misfolded proteins JO - J Cell Biol VL - 143 UR - https://doi.org/10.1083/jcb.143.7.1883 DO - 10.1083/jcb.143.7.1883 ID - Johnston1998 ER - TY - JOUR AU - Layfield, R. AU - Cavey, J. R. AU - Lowe, J. PY - 2003 DA - 2003// TI - Role of ubiquitin-mediated proteolysis in the pathogenesis of neurodegenerative disorders JO - Ageing Res Rev VL - 2 UR - https://doi.org/10.1016/S1568-1637(03)00025-4 DO - 10.1016/S1568-1637(03)00025-4 ID - Layfield2003 ER - TY - JOUR AU - Upadhya, S. C. AU - Hegde, A. PY - 2005 DA - 2005// TI - Ubiquitin-proteasome pathway components as therapeutic targets for CNS maladies JO - Curr Pharm Des VL - 11 UR - https://doi.org/10.2174/138161205774580651 DO - 10.2174/138161205774580651 ID - Upadhya2005 ER - TY - JOUR AU - Bingol, B. AU - Schuman, E. PY - 2005 DA - 2005// TI - Synaptic protein degradation by the ubiquitin proteasome system JO - Curr Opin Neurobiol VL - 15 UR - https://doi.org/10.1016/j.conb.2005.08.016 DO - 10.1016/j.conb.2005.08.016 ID - Bingol2005 ER - TY - JOUR AU - Speese, S. D. AU - Trotta, N. AU - Rodesch, C. K. AU - Aravamudan, B. AU - Broadie, K. PY - 2003 DA - 2003// TI - The ubiquitin proteasome system acutely regulates presynaptic protein turnover and synaptic efficacy JO - Curr Biol VL - 13 UR - https://doi.org/10.1016/S0960-9822(03)00338-5 DO - 10.1016/S0960-9822(03)00338-5 ID - Speese2003 ER - TY - JOUR AU - Upadhya, S. C. AU - Smith, T. K. AU - Hegde, A. PY - 2004 DA - 2004// TI - Ubiquitin-proteasome-mediated CREB repressor degradation during induction of long-term facilitation JO - J Neurochem VL - 91 UR - https://doi.org/10.1111/j.1471-4159.2004.02707.x DO - 10.1111/j.1471-4159.2004.02707.x ID - Upadhya2004 ER - TY - JOUR AU - Hegde, A. N. AU - Goldberg, A. L. AU - Schwartz, J. PY - 1993 DA - 1993// TI - Regulatory subunits of cAMP-dependent protein kinases are degraded after conjugation to ubiquitin: a molecular mechanism underlying long-term synaptic plasticity JO - Proc Natl Acad Sci U S A VL - 90 UR - https://doi.org/10.1073/pnas.90.16.7436 DO - 10.1073/pnas.90.16.7436 ID - Hegde1993 ER - TY - JOUR AU - Hegde, A. N. AU - Inokuchi, K. AU - Pei, W. AU - Casadio, A. AU - Ghirardi, M. AU - Chain, D. G. PY - 1997 DA - 1997// TI - Ubiquitin C-terminal hydrolase is an immediate-early gene essential for long-term facilitation in Aplysia JO - Cell VL - 89 UR - https://doi.org/10.1016/S0092-8674(00)80188-9 DO - 10.1016/S0092-8674(00)80188-9 ID - Hegde1997 ER - TY - JOUR AU - Gong, B. AU - Cao, Z. AU - Zheng, P. AU - Vitolo, O. V. AU - Liu, S. AU - Staniszewski, A. PY - 2006 DA - 2006// TI - Ubiquitin Hydrolase Uch-L1 Rescues beta-Amyloid-Induced Decreases in Synaptic Function and Contextual Memory JO - Cell VL - 126 UR - https://doi.org/10.1016/j.cell.2006.06.046 DO - 10.1016/j.cell.2006.06.046 ID - Gong2006 ER - TY - JOUR AU - Ichihara, N. AU - Wu, J. AU - Chui, D. H. AU - Yamazaki, K. AU - Wakabayashi, T. AU - Kikuchi, T. PY - 1995 DA - 1995// TI - Axonal Degeneration Promotes Abnormal Accumulation of Amyloid Beta-Protein in Ascending Gracile Tract of Gracile Axonal Dystrophy (Gad) Mouse JO - Brain Research VL - 695 UR - https://doi.org/10.1016/0006-8993(95)00729-A DO - 10.1016/0006-8993(95)00729-A ID - Ichihara1995 ER - TY - JOUR AU - Wu, J. AU - Ichihara, N. AU - Chui, D. H. AU - Yamazaki, K. AU - Kikuchi, T. PY - 1995 DA - 1995// TI - [Ubiquitin immunoreactivity in the central nervous system of gracile axonal dystrophy (GAD) mouse] JO - No To Shinkei VL - 47 ID - Wu1995 ER - TY - JOUR AU - Osaka, H. AU - Wang, Y. L. AU - Takada, K. AU - Takizawa, S. AU - Setsuie, R. AU - Li, H. PY - 2003 DA - 2003// TI - Ubiquitin carboxy-terminal hydrolase L1 binds to and stabilizes monoubiquitin in neuron JO - Hum Mol Genet VL - 12 UR - https://doi.org/10.1093/hmg/ddg211 DO - 10.1093/hmg/ddg211 ID - Osaka2003 ER - TY - JOUR AU - Barrachina, M. AU - Castano, E. AU - Dalfo, E. AU - Maes, T. AU - Buesa, C. AU - Ferrer, I. PY - 2006 DA - 2006// TI - Reduced ubiquitin C-terminal hydrolase-1 expression levels in dementia with Lewy bodies JO - Neurobiol Dis VL - 22 UR - https://doi.org/10.1016/j.nbd.2005.11.005 DO - 10.1016/j.nbd.2005.11.005 ID - Barrachina2006 ER - TY - JOUR AU - Choi, J. AU - Levey, A. I. AU - Weintraub, S. T. AU - Rees, H. D. AU - Gearing, M. AU - Chin, L. S. PY - 2004 DA - 2004// TI - Oxidative modifications and down-regulation of ubiquitin carboxyl-terminal hydrolase L1 associated with idiopathic Parkinson's and Alzheimer's diseases JO - J Biol Chem VL - 279 UR - https://doi.org/10.1074/jbc.M314124200 DO - 10.1074/jbc.M314124200 ID - Choi2004 ER - TY - JOUR AU - Xue, S. AU - Jia, J. PY - 2006 DA - 2006// TI - Genetic association between Ubiquitin Carboxy-terminal Hydrolase-L1 gene S18Y polymorphism and sporadic Alzheimer's disease in a Chinese Han population JO - Brain Res VL - 1087 UR - https://doi.org/10.1016/j.brainres.2006.02.121 DO - 10.1016/j.brainres.2006.02.121 ID - Xue2006 ER - TY - JOUR AU - van Leeuwen, F. W. AU - van, T. P. AU - Sonnemans, M. A. AU - Hobo, B. AU - Mann, D. M. AU - Van, B. C. PY - 2006 DA - 2006// TI - Frameshift proteins in autosomal dominant forms of Alzheimer disease and other tauopathies JO - Neurology VL - 66 UR - https://doi.org/10.1212/01.wnl.0000193882.46003.6d DO - 10.1212/01.wnl.0000193882.46003.6d ID - van Leeuwen2006 ER - TY - JOUR AU - Wang, L. N. AU - Zhu, M. W. AU - Gui, Q. P. AU - Li, X. PY - 2003 DA - 2003// TI - [An analysis of the causes of dementia in 383 elderly autopsied cases] JO - Zhonghua Nei Ke Za Zhi VL - 42 ID - Wang2003 ER - TY - JOUR AU - Song, S. AU - Kim, S. Y. AU - Hong, Y. M. AU - Jo, D. G. AU - Lee, J. Y. AU - Shim, S. M. PY - 2003 DA - 2003// TI - Essential role of E2-25K/Hip-2 in mediating amyloid-beta neurotoxicity JO - Mol Cell VL - 12 UR - https://doi.org/10.1016/j.molcel.2003.08.005 DO - 10.1016/j.molcel.2003.08.005 ID - Song2003 ER - TY - JOUR AU - Shringarpure, R. AU - Grune, T. AU - Sitte, N. AU - Davies, K. PY - 2000 DA - 2000// TI - 4-Hydroxynonenal-modified amyloid-beta peptide inhibits the proteasome: possible importance in Alzheimer's disease JO - Cell Mol Life Sci VL - 57 UR - https://doi.org/10.1007/PL00000660 DO - 10.1007/PL00000660 ID - Shringarpure2000 ER - TY - JOUR AU - Gregori, L. AU - Hainfeld, J. F. AU - Simon, M. N. AU - Goldgaber, D. PY - 1997 DA - 1997// TI - Binding of amyloid beta protein to the 20 S proteasome JO - J Biol Chem VL - 272 UR - https://doi.org/10.1074/jbc.272.1.58 DO - 10.1074/jbc.272.1.58 ID - Gregori1997 ER - TY - JOUR AU - Almeida, C. G. AU - Takahashi, R. H. AU - Gouras, G. PY - 2006 DA - 2006// TI - Beta-amyloid accumulation impairs multivesicular body sorting by inhibiting the ubiquitin-proteasome system JO - J Neurosci VL - 26 UR - https://doi.org/10.1523/JNEUROSCI.5078-05.2006 DO - 10.1523/JNEUROSCI.5078-05.2006 ID - Almeida2006 ER - TY - CHAP AU - Wirths, O. AU - Weis, J. AU - Kayed, R. AU - Saido, T. C. AU - Bayer, T. PY - 2006 DA - 2006// TI - Age-dependent axonal degeneration in an Alzheimer mouse model BT - Neurobiol Aging ID - Wirths2006 ER - TY - JOUR AU - Wirths, O. AU - Weis, J. AU - Szczygielski, J. AU - Multhaup, G. AU - Bayer, T. PY - 2006 DA - 2006// TI - Axonopathy in an APP/PS1 transgenic mouse model of Alzheimer's disease JO - Acta Neuropathol (Berl) VL - 111 UR - https://doi.org/10.1007/s00401-006-0041-4 DO - 10.1007/s00401-006-0041-4 ID - Wirths2006 ER - TY - JOUR AU - Keller, J. N. AU - Hanni, K. B. AU - Markesbery, W. PY - 2000 DA - 2000// TI - Impaired proteasome function in Alzheimer's disease JO - J Neurochem VL - 75 UR - https://doi.org/10.1046/j.1471-4159.2000.0750436.x DO - 10.1046/j.1471-4159.2000.0750436.x ID - Keller2000 ER - TY - JOUR AU - Keck, S. AU - Nitsch, R. AU - Grune, T. AU - Ullrich, O. PY - 2003 DA - 2003// TI - Proteasome inhibition by paired helical filament-tau in brains of patients with Alzheimer's disease JO - J Neurochem VL - 85 UR - https://doi.org/10.1046/j.1471-4159.2003.01642.x DO - 10.1046/j.1471-4159.2003.01642.x ID - Keck2003 ER - TY - STD TI - Bossy-Wetzel E, Schwarzenbacher R, Lipton S: Molecular pathways to neurodegeneration. Nat Med. 2004, S2-S9. 10.1038/nm1067. 10 Suppl ID - ref56 ER - TY - JOUR AU - Dickey, C. A. AU - Yue, M. AU - Lin, W. L. AU - Dickson, D. W. AU - Dunmore, J. H. AU - Lee, W. C. PY - 2006 DA - 2006// TI - Deletion of the ubiquitin ligase CHIP leads to the accumulation, but not the aggregation, of both endogenous phospho- and caspase-3-cleaved tau species JO - J Neurosci VL - 26 UR - https://doi.org/10.1523/JNEUROSCI.0746-06.2006 DO - 10.1523/JNEUROSCI.0746-06.2006 ID - Dickey2006 ER - TY - JOUR AU - Sahara, N. AU - Murayama, M. AU - Mizoroki, T. AU - Urushitani, M. AU - Imai, Y. AU - Takahashi, R. PY - 2005 DA - 2005// TI - In vivo evidence of CHIP up-regulation attenuating tau aggregation JO - J Neurochem VL - 94 UR - https://doi.org/10.1111/j.1471-4159.2005.03272.x DO - 10.1111/j.1471-4159.2005.03272.x ID - Sahara2005 ER - TY - JOUR AU - Babu, J. R. AU - Geetha, T. AU - Wooten, M. PY - 2005 DA - 2005// TI - Sequestosome 1/p62 shuttles polyubiquitinated tau for proteasomal degradation JO - J Neurochem VL - 94 UR - https://doi.org/10.1111/j.1471-4159.2005.03181.x DO - 10.1111/j.1471-4159.2005.03181.x ID - Babu2005 ER - TY - JOUR AU - van Leeuwen, F. W. AU - de Kleijn, D. P. AU - van den Hurk, H. H. AU - Neubauer, A. AU - Sonnemans, M. A. AU - Sluijs, J. A. PY - 1998 DA - 1998// TI - Frameshift mutants of beta amyloid precursor protein and ubiquitin-B in Alzheimer's and Down patients JO - Science VL - 279 UR - https://doi.org/10.1126/science.279.5348.242 DO - 10.1126/science.279.5348.242 ID - van Leeuwen1998 ER - TY - JOUR AU - Lam, Y. A. AU - Pickart, C. M. AU - Alban, A. AU - Landon, M. AU - Jamieson, C. AU - Ramage, R. PY - 2000 DA - 2000// TI - Inhibition of the ubiquitin-proteasome system in Alzheimer's disease JO - Proc Natl Acad Sci U S A VL - 97 UR - https://doi.org/10.1073/pnas.170173897 DO - 10.1073/pnas.170173897 ID - Lam2000 ER - TY - JOUR AU - de, P. R. AU - Fischer, D. F. AU - Maat-Schieman, M. L. AU - Hobo, B. AU - de Vos, R. A. AU - Brunt, E. R. PY - 2004 DA - 2004// TI - Accumulation of aberrant ubiquitin induces aggregate formation and cell death in polyglutamine diseases JO - Hum Mol Genet VL - 13 UR - https://doi.org/10.1093/hmg/ddh188 DO - 10.1093/hmg/ddh188 ID - de2004 ER - TY - JOUR AU - Lindsten, K. AU - de Vrij, F. M. AU - Verhoef, L. G. AU - Fischer, D. F. AU - van Leeuwen, F. W. AU - Hol, E. M. PY - 2002 DA - 2002// TI - Mutant ubiquitin found in neurodegenerative disorders is a ubiquitin fusion degradation substrate that blocks proteasomal degradation JO - J Cell Biol VL - 157 UR - https://doi.org/10.1083/jcb.200111034 DO - 10.1083/jcb.200111034 ID - Lindsten2002 ER - TY - JOUR AU - Kim, T. W. AU - Pettingell, W. H. AU - Hallmark, O. G. AU - Moir, R. D. AU - Wasco, W. AU - Tanzi, R. PY - 1997 DA - 1997// TI - Endoproteolytic cleavage and proteasomal degradation of presenilin 2 in transfected cells JO - J Biol Chem VL - 272 UR - https://doi.org/10.1074/jbc.272.17.11006 DO - 10.1074/jbc.272.17.11006 ID - Kim1997 ER - TY - JOUR AU - Marambaud, P. AU - Zhao, H. AU - Davies, P. PY - 2005 DA - 2005// TI - Resveratrol promotes clearance of Alzheimer's disease amyloid-beta peptides JO - J Biol Chem VL - 280 UR - https://doi.org/10.1074/jbc.M508246200 DO - 10.1074/jbc.M508246200 ID - Marambaud2005 ER - TY - JOUR AU - Adams, J. AU - Kauffman, M. PY - 2004 DA - 2004// TI - Development of the proteasome inhibitor Velcade (Bortezomib) JO - Cancer Invest VL - 22 UR - https://doi.org/10.1081/CNV-120030218 DO - 10.1081/CNV-120030218 ID - Adams2004 ER - TY - JOUR AU - Upadhya, S. C. AU - Ding, L. AU - Smith, T. K. AU - Hegde, A. PY - 2006 DA - 2006// TI - Differential regulation of proteasome activity in the nucleus and the synaptic terminals JO - Neurochem Int VL - 48 UR - https://doi.org/10.1016/j.neuint.2005.11.003 DO - 10.1016/j.neuint.2005.11.003 ID - Upadhya2006 ER - TY - JOUR AU - Saltini, G. AU - Dominici, R. AU - Lovati, C. AU - Cattaneo, M. AU - Michelini, S. AU - Malferrari, G. PY - 2006 DA - 2006// TI - A novel polymorphism in SEL1L confers susceptibility to Alzheimer's disease JO - Neurosci Lett VL - 398 UR - https://doi.org/10.1016/j.neulet.2005.12.038 DO - 10.1016/j.neulet.2005.12.038 ID - Saltini2006 ER - TY - JOUR AU - von Rotz, R. C. AU - Kins, S. AU - Hipfel, R. AU - von der, K. H. AU - Nitsch, R. PY - 2005 DA - 2005// TI - The novel cytosolic RING finger protein dactylidin is up-regulated in brains of patients with Alzheimer's disease JO - Eur J Neurosci VL - 21 UR - https://doi.org/10.1111/j.1460-9568.2005.03977.x DO - 10.1111/j.1460-9568.2005.03977.x ID - von Rotz2005 ER - TY - JOUR AU - Klionsky, D. J. AU - Emr, S. PY - 2000 DA - 2000// TI - Autophagy as a regulated pathway of cellular degradation JO - Science VL - 290 UR - https://doi.org/10.1126/science.290.5497.1717 DO - 10.1126/science.290.5497.1717 ID - Klionsky2000 ER - TY - JOUR AU - Murayama, O. AU - Tomita, T. AU - Nihonmatsu, N. AU - Murayama, M. AU - Sun, X. AU - Honda, T. PY - 1999 DA - 1999// TI - Enhancement of amyloid beta 42 secretion by 28 different presenilin 1 mutations of familial Alzheimer's disease JO - Neurosci Lett VL - 265 UR - https://doi.org/10.1016/S0304-3940(99)00187-1 DO - 10.1016/S0304-3940(99)00187-1 ID - Murayama1999 ER - TY - STD TI - Republished from Current BioData's Targeted Proteins database (TPdb; http://www.targetedproteinsdb.com). UR - http://www.targetedproteinsdb.com ID - ref72 ER -