Skip to main content
Figure 2 | BMC Biochemistry

Figure 2

From: Revalidation and rationale for high pKa values of unconjugated bilirubin

Figure 2

Two-dimensional representation of the structural environment of the carboxyl groups of unconjugated bilirubin. Left panel shows the three internal hydrogen bonds (||||||) that involve each -COOH group of unionized UCB diacid. All the donors and acceptors of the hydrogen bonds belong to the UCB molecule. With ionization of the -CO-OH group (right panel), the H-bond involving the -OH group is lost, but the two H-bonds remain that involve the carbonyl group of the carboxylate anion (-CO-O-).

Back to article page