Figure 1
From: Binding to DPF-motif by the POB1 EH domain is responsible for POB1-Eps15 interaction
Domain organization of human POB1 and human Eps15 proteins. The domain structure of hPOB1 (Swiss Prot entry: Q8NFH8) and of hEps15 (Swiss Prot entry: P42567) and their binding partners are illustrated ([17, 26, 30-36]). Abbreviations: EH, Eps15 Homology; RalBP1-BD, RalA binding protein 1-binding protein; CC, Coiled-Coil region; UIM, Ubiquitin Interacting Motif; Epsin, Eps-15 Interacting protein; Eps-15, Epidermal growth factor receptor pathwat substrate 15; Grb2, growth factor receptor-bound protein 2; PAG2, Paxillin-associated protein with ARFGAP activity 2; AP180, Clathrin coat assembly protein AP180; Hrb, HIV-1 Rev-binding protein.