Figure 3From: Metabolic signature of breast cancer cell line MCF-7: profiling of modified nucleosides via LC-IT MS couplingConstant neutral loss (CNL) chromatograms of a MCF-7 cell culture supernatant sample. The different CNL amu values are characteristic for the various ribose structures of the analyzed metabolites, lost as a neutral moiety in the MS/MS fragmentation of the labile C-N-glycosidic bond between sugar and base. Numbers refer to metabolites listed in table 1. ψ (no characteristic neutral loss because of stable C-C-glycosidic bond) and IAA-R (not detectable in supernatants of MCF-7) are not shown.Back to article page