Table 1 Model pKa values for all protein basic and acidic titratable groups. See reference 5.
| Â | Â | No. in Study | Â | |
|---|---|---|---|---|
Titratable Group | pKmodelValue | LARGE | SMALL | Mean pKexpValue |
N-Termini | 7.5 | - | - | - |
C-Termini | 3.8 | - | - | - |
Arg | 12 | 1 | 1 | - |
Asp | 4 | 143 | 112 | 3.5 |
Cys | 9.5 | 11 | 4 | 6.6 |
Glu | 4.4 | 126 | 105 | 4.3 |
His | 6.3 | 130 | 24 | 6.4 |
Lys | 10.4 | 57 | 23 | 9.6 |
Tyr | 10 | 26 | 16 | 9.5 |