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Table 3 IC50 calcium displacement values for various peptides/proteins. The molecular weights and the IC50-values (concentration of the peptides/proteins necessary to displace 50% of the calcium adsorbed to LPSF515 monolayers) are shown. Bathing solution: 12.5 μM calcium doped with radioactive 45Ca2+ resulting in a relative β-activity of 250 Bq/ml, buffered with 5 mM HEPES, and adjusted to pH7; the LPSF515 concentration was 9.6 nmol (160 nM).

From: Calcium adsorption and displacement: characterization of lipid monolayers and their interaction with membrane-active peptides/proteins

Peptide/Protein MW IC50/μM
rCAP18 3801 0.22
lactoferrin 78922 0.12
rBPI21 21063 0.16
PMB 1200 0.84
PMBN 963 0.76
lactalbumin 66000 1
lysozyme 14400 6.9
rHSA 66000 14
hemoglobin 64000 32