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Table 1 ZP-N proteins

From: The PLAC1-homology region of the ZP domain is sufficient for protein polymerisation

Species

Protein name (accession number)

Amino acid number

HMM search*

Signal peptide†

Expression evidence

Reference(s)

Putative homolog(s)

C. elegans

F55A4.10 (AAL06028.2)

633

3.7e-13; 62.3; 31–126 (4)

0.999 (1–18); 11.327 (1–18)

ESTs (AU201804, CB402430), microarray (WormBase WBGene00018861)

[56]

-

D. melanogaster

Papillote/CG2467 (NP_727583.1)

963

4e-15; 69.0; 80–167 (4)

0.999 (1–32); 11.890 (1–32)

mRNA (AY862156), immunohisto-chemistry and Western blot [16], in situ hybridization (BDGP CG2467; [17])

[16, 17]

EAL32136.1 (D. pseudoobscura)

D. melanogaster

CG16798 (NP_610030.1)

561

9.9e-12; 57.7; 255–343 (4)

1.000 (1–28); 13.662 (1–28)

mRNA (AY122225), in situ hybridization (BDGP CG16798; [17])

[17]

SNAP00000007590 (A. gambiae)

D. melanogaster

CG10005 (NP_650137.3)

231

4.3e-17; 75.5; 59–151 (4)

0.999 (1–24); 6.625 (1–19)

mRNA (AY113516), microarray (BDGP CG10005)

-

EAL28621.1 (D. pseudoobscura), SNAP00000007531 (A. gambiae)

C. carpio

ZP1 § (CAA96573.1)

555

8.4e-29; 114.4; 381–482 (4)

0.999 (1–19); 6.833 (1–19)

MRNA (Z72492), Northern blot, in situ hydridization, immuno-histochemistry, Western blot [41]

[41]

-

M. musculus

Oosp1 (NP_579931.1)

202

3.2e-07; 42.7; 30–119 (4)

1.000 (1–21); 8.733 (1–21)

mRNA (AF420487), Northern blot, in situ hydridization [18]

[18, 19]

ENSRNOP00000028498 (R. norvegicus)

M. musculus

LOC225923/Oosp3 (NP_001028455.1)

194

1.2; 19.9; 28–117 (4)

1.000 (1–21); 8.275 (1–21)

mRNA (NM_001033283), RT-PCR, in situ hybridization [19]

[19]

-

H. sapiens

PLAC1 (NP_068568.1)

212

8.7e-11; 54.6; 29–119 (4)

0.999 (1–22); 7.539 (1–23)

MRNA (BC022335), Northern blot, in situ hydridizationm [11, 12, 15]

[11, 12, 15]

ENSPTRP00000038397 (P. troglodytes), ENSBTAP00000008260 (B. taurus), ENSCAFP00000027834 (C. familiaris), NP_001020065 (R. norvegicus), NP_062411.1 (M. musculus)

H. sapiens

LOC219990/Oosp2 (NP_776162.2)

158

0.0067; 28.4; 25–116 (4)

0.997 (1–17); 10.702 (1–17)

MRNA (NM_173801)

[19, 57]

ENSPTRP00000006381 (P. troglodytes) NP_001032723.1 (M. musculus)

  1. * E-value; bit score; matched aa (number of Cys). Calibrated expectation values are relative to the NCBI non-redundant protein database (2308679 sequences at the time of the search).
  2. †SignalP probability (aa); SigCleave score (aa).
  3. §This protein is referred to as ZP2 in ref. 41. However, because it contains a trefoil domain immediately before the ZP domain, it should be regarded as a member of the ZP1 family.