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Table 2 Determination of substrate binding sites in amino acid sequences of lysozyme families

From: Pattern similarity study of functional sites in protein sequences: lysozymes and cystatins

 

Potential sites

Hen 1

55(35)E

70(42)A

77(48)D

84(55)I

90(61)R

102(72)S

117(83)L

 

118(111)W

 

.81/.71

.79/.53

.34/.65

1.0/.41

.56/.58

.78/.56

.61/.42

 

.66/.35

Hen 2

36S

45R

49G

56L

62W

73R

90A

100S

112R

 

.82/.71

.86/.44

.79/.47

1.0/.39

.59/.58

.91/.47

.98/.41

.55/.46

.76/.29

Human 1

54(34)W

70(42)A

77(49)D

84(56)I

90(62)R

102(73)A

116(83)A

 

118(112)W

 

.48/.52

.42/.51

.34/.65

.91/.47

.50/.61

.80/.32

.61/.46

 

.89/.45

Human 2

27N

43T

50R

57F

63Y

74V

84L

101R

117Q

 

.56/.39

.56/.51

.61/.47

1.0/.45

.55/.61

.72/.33

.48/.47

.58/.29

.79/.45

Goose

43(73)I

99(93)L

119(113)I

143(133)S

181(143)G

201(163)G

   
 

.85/.31

.76/.34

.67/.46

.81/.55

.82/.36

.81/.58

   

T4

6(6)M

16(16)K

53(49)A

66(57)V

75(66)L

94(85)K

123(112)A

186(136)S

207(153)F

 

.74/.34

.99/.38

.78/.30

1.0/.42

.52/.54

.67/.38

.73/.45

.58/.51

.78/.36

CH

40(35)T

47(42)D

55(50)T

80(74)A

92(86)W

124(118)T

153(147)C

186(180)T

 
 

1.0/.58

.63/.52

.80/.51

.51/.44

.73/.49

.83/.59

.51/.56

.56/.54

 
  1. The first/second digits are similarity constants and average hydrogen bond index values of binding site with segments of sox residues beginning with the positions shown. Bold digits show more likely binding sites than non-bold digits.
  2. Hen 1 and Human 1: from the alignment shown in Figure 2; Hen 2 and Human 2; from the alignment of the lysozyme C family exclusively.