TY - CHAP AU - Coleman, R. A. AU - Kennedy, I. AU - Humphrey, P. P. A. AU - Bunce, K. AU - Kumley, P. ED - Hansch, C. ED - Sammes, P. G. ED - Taylor, J. B. ED - Emmett, J. C. PY - 1990 DA - 1990// BT - Prostaglandin and their receptor in comprehensive medicinal chemistry PB - Pergamon Press CY - Oxford ID - Coleman1990 ER - TY - JOUR AU - Ushikubi, F. AU - Nakajima, M. AU - Hirata, M. AU - Okuma, M. AU - Fujiwara, M. AU - Narumiya, S. PY - 1989 DA - 1989// TI - Purification of the thromboxane A2/prostagiandin H2 receptor from human blood platelets JO - J Biol Chem VL - 264 ID - Ushikubi1989 ER - TY - JOUR AU - Hirata, M. AU - Hayashi, Y. AU - Ushikubi, F. AU - Yokata, Y. AU - Kageyama, R. AU - Nakanishi, S. AU - Narumiya, S. PY - 1991 DA - 1991// TI - Cloning and expression of cDNA for a human thromboxane A2 receptor JO - Nature VL - 349 UR - https://doi.org/10.1038/349617a0 DO - 10.1038/349617a0 ID - Hirata1991 ER - TY - JOUR AU - Negishi, M. AU - Sugimoto, Y. AU - Ichikawa, A. PY - 1995 DA - 1995// TI - Molecular mechanisms of diverse actions of prostanoid receptors JO - Biochim Biophys Acta VL - 1259 UR - https://doi.org/10.1016/0005-2760(95)00146-4 DO - 10.1016/0005-2760(95)00146-4 ID - Negishi1995 ER - TY - JOUR AU - Funk, C. D. AU - Furci, L. AU - Moran, N. AU - Fitzgerald, G. A. PY - 1993 DA - 1993// TI - Point mutation in the seventh hydrophobic domain of the human thromboxane A2 receptor allows discrimination between agonist and antagonist binding sites JO - Mol Pharmacol VL - 44 ID - Funk1993 ER - TY - JOUR AU - Yamamoto, Y. AU - Kamiya, K. AU - Terao, S. PY - 1993 DA - 1993// TI - Modeling of human thromboxane A2 receptor and analysis of the receptor-ligand interaction JO - J Med Chem VL - 36 UR - https://doi.org/10.1021/jm00059a005 DO - 10.1021/jm00059a005 ID - Yamamoto1993 ER - TY - JOUR AU - Chiang, N. AU - Kan, W. M. AU - Tai, H. H. PY - 1996 DA - 1996// TI - Site-directed mutagenesis of cysteinyl and serine residues of human thromboxane A2 receptor in insect cells JO - Arch Biochem Biophys VL - 334 UR - https://doi.org/10.1006/abbi.1996.0423 DO - 10.1006/abbi.1996.0423 ID - Chiang1996 ER - TY - JOUR AU - Breyer, R. M. AU - Audoly, L. PY - 1997 DA - 1997// TI - The second extracellular loop of the prostaglandin EP3 receptor is an essential determinant of ligand selectivity JO - J Biol Chem VL - 272 UR - https://doi.org/10.1074/jbc.272.21.13475 DO - 10.1074/jbc.272.21.13475 ID - Breyer1997 ER - TY - JOUR AU - Turek, J. W. AU - Halmos, T. AU - Sullivan, N. L. AU - Antonakis, K. AU - Le Breton, G. C. PY - 2002 DA - 2002// TI - Mapping of a ligand-binding site for the human thromboxane A2 receptor protein JO - J Biol Chem VL - 277 UR - https://doi.org/10.1074/jbc.M105872200 DO - 10.1074/jbc.M105872200 ID - Turek2002 ER - TY - JOUR AU - So, S. P. AU - Wu, J. AU - Huang, G. AU - Huang, A. AU - Li, D. AU - Ruan, K. H. PY - 2003 DA - 2003// TI - Identification of residues important for ligand binding of thromboxane A2 receptor in the second extracellular loop using the NMR experiment-guided mutagenesis approach JO - J Biol Chem VL - 278 UR - https://doi.org/10.1074/jbc.M209337200 DO - 10.1074/jbc.M209337200 ID - So2003 ER - TY - JOUR AU - Perlman, J. H. AU - Colson, A. O. AU - Jain, R. AU - Czyzewski, B. AU - Cohen, L. A. AU - Osman, R. AU - Gershengorn, M. C. PY - 1997 DA - 1997// TI - Role of the extracellular loops of the thyrotropin-releasing hormone receptor: evidence for an initial interaction with thyrotropin-releasing hormone JO - Biochemistry VL - 36 UR - https://doi.org/10.1021/bi9713310 DO - 10.1021/bi9713310 ID - Perlman1997 ER - TY - JOUR AU - Hoffmann, C. AU - Moro, S. AU - Nicholas, R. A. AU - Harden, T. K. AU - Jacobson, K. A. PY - 1999 DA - 1999// TI - The role of amino acids in extracellular loops of the human P2Y1 receptor in surface expression and activation processes JO - J Biol Chem VL - 274 UR - https://doi.org/10.1074/jbc.274.21.14639 DO - 10.1074/jbc.274.21.14639 ID - Hoffmann1999 ER - TY - JOUR AU - Olah, M. E. AU - Jacobson, K. A. AU - Stiles, G. L. PY - 1994 DA - 1994// TI - Role of the second extracellular loop of adenosine receptors in agonist and antagonist binding: Analysis of chimeric A1/A3 adenosine receptors JO - J Biol Chem VL - 269 ID - Olah1994 ER - TY - JOUR AU - Kim, J. AU - Jiang, Q. AU - Glashofer, M. AU - Yehle, S. AU - Wess, J. AU - Jacobson, K. A. PY - 1996 DA - 1996// TI - Glutamate residues in the second extracellular loop of the human A2a adenosine receptor are required for ligand recognition JO - Mol Pharmacol VL - 49 ID - Kim1996 ER - TY - JOUR AU - Zhao, M. M. AU - Hwa, J. AU - Perez, D. M. PY - 1996 DA - 1996// TI - Identification of critical extracellular loop residues involved in alpha 1-adrenergic receptor subtype-selective antagonist binding JO - Mol Pharmacol VL - 50 ID - Zhao1996 ER - TY - JOUR AU - Henderson, R. AU - Baldwin, J. M. AU - Ceska, T. A. AU - Zemlin, F. AU - Beckmann, E. AU - Downing, K. H. PY - 1990 DA - 1990// TI - Model for the structure of bacteriorhodopsin based on high-resolution electron cryomicroscopy JO - J Mol Biol VL - 213 UR - https://doi.org/10.1016/S0022-2836(05)80271-2 DO - 10.1016/S0022-2836(05)80271-2 ID - Henderson1990 ER - TY - JOUR AU - Gregorieff, N. AU - Ceska, T. A. AU - Downing, K. H. AU - Baldwin, J. M. AU - Henderson, R. PY - 1996 DA - 1996// TI - Electron crystallographic refinement of the structure of bacteriorhodopsin JO - J Mol Biol VL - 259 UR - https://doi.org/10.1006/jmbi.1996.0328 DO - 10.1006/jmbi.1996.0328 ID - Gregorieff1996 ER - TY - JOUR AU - Edman, K. AU - Nollert, P. AU - Royant, A. AU - Belrhali, H. AU - Pebay-Peyroula, E. AU - Hajdu, J. AU - Neutze, R. AU - Landau, E. M. PY - 1999 DA - 1999// TI - High resolution x-ray structure of an early intermediate in the bacteriorhodopsin photocycle JO - Nature VL - 401 UR - https://doi.org/10.1038/44623 DO - 10.1038/44623 ID - Edman1999 ER - TY - JOUR AU - Luecke, H. AU - Schobert, B. AU - Richter, H. T. AU - Cartailler, J. P. AU - Lanyi, J. K. PY - 1999 DA - 1999// TI - Structure of bacteriorhodopsin at 1.55Angstrom resolution JO - J Mol Biol VL - 291 UR - https://doi.org/10.1006/jmbi.1999.3027 DO - 10.1006/jmbi.1999.3027 ID - Luecke1999 ER - TY - JOUR AU - Findlay, J. AU - Eliopoulos, E. PY - 1990 DA - 1990// TI - Three-dimensional modeling of G protein-linked receptors JO - Trends Pharmacol Sci VL - 12 UR - https://doi.org/10.1016/0165-6147(90)90050-I DO - 10.1016/0165-6147(90)90050-I ID - Findlay1990 ER - TY - JOUR AU - Grotzinger, J. AU - Engels, M. AU - Jacoby, E. AU - Wollmer, A. AU - Strassburger, W. PY - 1991 DA - 1991// TI - A model for the C5a receptor and for its interaction with the ligand JO - Protein Eng VL - 7 UR - https://doi.org/10.1093/protein/4.7.767 DO - 10.1093/protein/4.7.767 ID - Grotzinger1991 ER - TY - JOUR AU - Hibert, M. F. AU - Trumppkallmeyer, S. AU - Bruinvels, A. AU - Hoflack, J. PY - 1991 DA - 1991// TI - 3-dimensional models of neurotransmitter G-binding protein-coupled receptors JO - Mol Pharmacol VL - 40 ID - Hibert1991 ER - TY - JOUR AU - Ijzerman, A. P. AU - Galen, J. V. AU - Jacobson, K. A. PY - 1992 DA - 1992// TI - Molecular modeling of adenosine receptors. I.The ligand binding site on the A1 receptor JO - Drug Des Discov VL - 9 ID - Ijzerman1992 ER - TY - JOUR AU - Lewell, X. Q. PY - 1992 DA - 1992// TI - A model of the adrenergic beta-2 receptor and binding sites for agonist and antagonist JO - Drug Des Discov VL - 9 ID - Lewell1992 ER - TY - JOUR AU - Cronet, P. AU - Sander, C. AU - Vriend, G. PY - 1993 DA - 1993// TI - Modeling of transmembrane 7helix bundles JO - Protein Eng VL - 6 UR - https://doi.org/10.1093/protein/6.1.59 DO - 10.1093/protein/6.1.59 ID - Cronet1993 ER - TY - JOUR AU - Sylte, I. AU - Edvardsen, O. AU - Dahl, S. G. PY - 1993 DA - 1993// TI - Molecular dynamics of the 5-HT1a receptor and ligands JO - Protein Eng VL - 6 UR - https://doi.org/10.1093/protein/6.7.691 DO - 10.1093/protein/6.7.691 ID - Sylte1993 ER - TY - JOUR AU - Zhang, D. Q. AU - Weinstein, H. PY - 1993 DA - 1993// TI - Signal transduction by a 5-HT2 receptor – a mechanistic hypothesis from molecular-dynamics simulations of the 3-dimensional model of the receptor complexed to ligands JO - J Med Chem VL - 36 UR - https://doi.org/10.1021/jm00059a021 DO - 10.1021/jm00059a021 ID - Zhang1993 ER - TY - JOUR AU - Van Rhee, A. M. AU - Fischer, P. J. M. AU - Van, G. AU - Jacobson, K. A. PY - 1995 DA - 1995// TI - Modeling the P2y purinoceptor using rhodopsin template JO - Drug Des Discov VL - 13 ID - Van Rhee1995 ER - TY - JOUR AU - Pogozheva, I. D. AU - Lomize, A. L. AU - Mosberg, H. I. PY - 1997 DA - 1997// TI - The transmembrane 7-alpha-bundle of rhodopsin: distance geometry calculations with hydrogen bonding constraints JO - Biophys J VL - 72 UR - https://doi.org/10.1016/S0006-3495(97)78842-8 DO - 10.1016/S0006-3495(97)78842-8 ID - Pogozheva1997 ER - TY - JOUR AU - Baldwin, J. M. PY - 1993 DA - 1993// TI - The probable arrangement of the helices in G protein-coupled receptors JO - EMBO J VL - 12 ID - Baldwin1993 ER - TY - JOUR AU - Herzyk, P. AU - Hubbard, R. E. PY - 1998 DA - 1998// TI - Combined biophysical and biochemical information confirms arrangement of transmembrane helices visible from the three-dimensional map of frog rhodopsin JO - J Mol Biol VL - 281 UR - https://doi.org/10.1006/jmbi.1998.1981 DO - 10.1006/jmbi.1998.1981 ID - Herzyk1998 ER - TY - JOUR AU - Konvicka, K. AU - Guarnieri, F. AU - Ballesteros, J. A. AU - Weinstein, H. PY - 1998 DA - 1998// TI - A proposed structure for transmembrane segment 7of G protein-coupled receptors incorporating an Asn-Pro/Asp-Pro motif JO - Biophys J VL - 75 UR - https://doi.org/10.1016/S0006-3495(98)77551-4 DO - 10.1016/S0006-3495(98)77551-4 ID - Konvicka1998 ER - TY - JOUR AU - Attwood, T. K. AU - Findlay, J. B. C. PY - 1993 DA - 1993// TI - Design of a discriminating fingerprint for G-protein-coupled receptors JO - Protein Eng VL - 6 UR - https://doi.org/10.1093/protein/6.2.167 DO - 10.1093/protein/6.2.167 ID - Attwood1993 ER - TY - JOUR AU - Schertler, G. F. X. AU - Villa, C. AU - Henderson, R. PY - 1993 DA - 1993// TI - Projection structure of rhodopsin JO - Nature VL - 362 UR - https://doi.org/10.1038/362770a0 DO - 10.1038/362770a0 ID - Schertler1993 ER - TY - JOUR AU - Schertler, G. F. X. AU - Hargrave, P. A. PY - 1995 DA - 1995// TI - Projection structure of frog rhodopsin in two crystal forms JO - Proc Natl Acad Sci USA VL - 92 UR - https://doi.org/10.1073/pnas.92.25.11578 DO - 10.1073/pnas.92.25.11578 ID - Schertler1995 ER - TY - JOUR AU - Davies, A. AU - Schertler, G. F. X. AU - Gowen, B. E. AU - Saibil, H. R. PY - 1996 DA - 1996// TI - Projection structure of an invertebrate rhodopsin JO - J Struct Biol VL - 117 UR - https://doi.org/10.1006/jsbi.1996.0067 DO - 10.1006/jsbi.1996.0067 ID - Davies1996 ER - TY - JOUR AU - Krebs, A. AU - Villa, C. AU - Edwards, P. C. AU - Schertler, G. F. X. PY - 1998 DA - 1998// TI - Characterization of an improved two dimensional p 22121 crystal from bovine rhodopsin JO - J Mol Biol VL - 282 UR - https://doi.org/10.1006/jmbi.1998.2070 DO - 10.1006/jmbi.1998.2070 ID - Krebs1998 ER - TY - JOUR AU - Unger, V. M. AU - Schertler, G. F. X. PY - 1995 DA - 1995// TI - Low-resolution structure of bovine rhodopsin determined by electron cryomicroscopy JO - Biophys J VL - 68 UR - https://doi.org/10.1016/S0006-3495(95)80354-1 DO - 10.1016/S0006-3495(95)80354-1 ID - Unger1995 ER - TY - JOUR AU - Unger, V. M. AU - Hargrave, P. A. AU - Baldwin, J. M. AU - Schertler, G. F. X. PY - 1997 DA - 1997// TI - Arrangement of rhodopsin transmembrane alpha-helices JO - Nature VL - 389 UR - https://doi.org/10.1038/38316 DO - 10.1038/38316 ID - Unger1997 ER - TY - JOUR AU - Katsuyama, M. AU - Sugimoto, Y. AU - Namba, T. AU - Irie, A. AU - Negishi, M. AU - Narumiya, S. AU - Ichikawa, A. PY - 1994 DA - 1994// TI - Cloning and expression of a cDNA for the human prostacyclin receptor JO - FEBS Lett VL - 344 UR - https://doi.org/10.1016/0014-5793(94)00355-6 DO - 10.1016/0014-5793(94)00355-6 ID - Katsuyama1994 ER - TY - JOUR AU - Ruan, K. H. AU - Milfeld, K. AU - Kulmacz, R. J. AU - Wu, K. K. PY - 1994 DA - 1994// TI - Comparison of the construction of a 3-D model for human thromboxane synthase using P450 cam and BM-3 as templates: implications for the substrate binding pocket JO - Protein Eng VL - 7 UR - https://doi.org/10.1093/protein/7.11.1345 DO - 10.1093/protein/7.11.1345 ID - Ruan1994 ER - TY - JOUR AU - Ruan, K. H. AU - Wu, J. AU - So, S. P. AU - Jenkins, L. A. PY - 2003 DA - 2003// TI - Evidence of the residues involved in ligand recognition in the second extracellular loop of the prostacyclin receptor characterized by high resolution 2D NMR techniques JO - Arch Biochem Biophys VL - 418 UR - https://doi.org/10.1016/S0003-9861(03)00401-6 DO - 10.1016/S0003-9861(03)00401-6 ID - Ruan2003 ER - TY - JOUR AU - Ruan, K. H. AU - Wu, J. AU - So, S. P. AU - Jenkins, L. A. AU - Ruan, C. H. PY - 2004 DA - 2004// TI - NMR structure of the thromboxane A2 receptor ligand recognition pocket JO - Eur J Biochem VL - 271 UR - https://doi.org/10.1111/j.1432-1033.2004.04232.x DO - 10.1111/j.1432-1033.2004.04232.x ID - Ruan2004 ER - TY - JOUR AU - Ruan, K. H. AU - So, S. P. AU - Wu, J. AU - Li, D. AU - Huang, A. AU - Kung, J. PY - 2001 DA - 2001// TI - Solution structure of the second extracellular loop of human thromboxane A2 receptor JO - Biochemistry VL - 40 UR - https://doi.org/10.1021/bi001867c DO - 10.1021/bi001867c ID - Ruan2001 ER - TY - JOUR AU - Wu, J. AU - So, S. P. AU - Ruan, K. H. PY - 2003 DA - 2003// TI - Solution structure of the third extracellular loop of human thromboxane A2 receptor JO - Arch Biochem Biophys VL - 414 UR - https://doi.org/10.1016/S0003-9861(03)00192-9 DO - 10.1016/S0003-9861(03)00192-9 ID - Wu2003 ER - TY - JOUR AU - Franzoni, L. AU - Nicastro, G. AU - Pertinhez, T. A. AU - Tato, M. AU - Nakaie, C. R. AU - Paiva, A. C. AU - Schreier, S. AU - Spisni, A. PY - 1997 DA - 1997// TI - Structure of the C-terminal fragment 300–320 of the rat angiotensin II AT1A receptor and its relevance with respect to G-protein coupling JO - J Biol Chem VL - 272 UR - https://doi.org/10.1074/jbc.272.15.9734 DO - 10.1074/jbc.272.15.9734 ID - Franzoni1997 ER - TY - JOUR AU - Anand-Srivastava, M. B. AU - Sehl, P. D. AU - Lowe, D. G. PY - 1996 DA - 1996// TI - Cytoplasmic domain of natriuretic peptide receptor-C inhibits adenylyl cyclase. Involvement of a pertussis toxin-sensitive G protein JO - J Biol Chem VL - 271 UR - https://doi.org/10.1074/jbc.271.32.19324 DO - 10.1074/jbc.271.32.19324 ID - Anand-Srivastava1996 ER - TY - JOUR AU - Dias, J. A. PY - 1996 DA - 1996// TI - Human follitropin heterodimerization and receptor binding structural motifs: identification and analysis by a combination of synthetic peptide and mutagenesis approaches JO - Mol Cell Endocrinol VL - 125 UR - https://doi.org/10.1016/S0303-7207(96)03947-0 DO - 10.1016/S0303-7207(96)03947-0 ID - Dias1996 ER - TY - JOUR AU - Takemoto, D. J. AU - Morrison, D. AU - Davis, L. C. AU - Takemoto, L. J. PY - 1986 DA - 1986// TI - C-terminal peptides of rhodopsin. Determination of the optimum sequence for recognition of retinal transducin JO - Biochem J VL - 235 UR - https://doi.org/10.1042/bj2350309 DO - 10.1042/bj2350309 ID - Takemoto1986 ER - TY - JOUR AU - Konig, B. AU - Arendt, A. AU - McDowell, J. H. AU - Kahlert, M. AU - Hargrave, P. A. AU - Hofmann, K. P. PY - 1989 DA - 1989// TI - Three cytoplasmic loops of rhodopsin interact with transducin JO - Proc Natl Acad Sci USA VL - 86 UR - https://doi.org/10.1073/pnas.86.18.6878 DO - 10.1073/pnas.86.18.6878 ID - Konig1989 ER - TY - JOUR AU - Okamoto, T. AU - Nishimoto, I. PY - 1992 DA - 1992// TI - Detection of G protein-activator regions in M4 subtype muscarinic, cholinergic, and alpha 2-adrenergic receptors based upon characteristics in primary structure JO - J Biol Chem VL - 267 ID - Okamoto1992 ER - TY - JOUR AU - Yeagle, P. L. AU - Alderfer, J. L. AU - Albert, A. D. PY - 1997 DA - 1997// TI - Three-dimensional structure of the cytoplasmic face of the G protein receptor rhodopsin JO - Biochemistry VL - 36 UR - https://doi.org/10.1021/bi970908a DO - 10.1021/bi970908a ID - Yeagle1997 ER - TY - JOUR AU - Okada, T. AU - Fujiyoshi, Y. AU - Silow, M. AU - Navarro, J. AU - Landau, E. M. AU - Shichida, Y. PY - 2002 DA - 2002// TI - Functional role of internal water molecules in rhodopsin revealed by X-ray crystallography JO - Proc Natl Acad Sci USA VL - 30 UR - https://doi.org/10.1073/pnas.082666399 DO - 10.1073/pnas.082666399 ID - Okada2002 ER - TY - STD TI - Biosym/MSI, Insight User Guide. 1995, San Diego, CA ID - ref54 ER - TY - JOUR AU - Hatae, N. AU - Yamaoka, K. AU - Sugimoto, Y. AU - Negishi, M. AU - Ichikawa, A. PY - 2002 DA - 2002// TI - Augmentation of receptor-mediated adenylyl cyclase activity by Gi-coupled prostaglandin receptor subtype EP3 in a Gbetagamma subunit-independent manner JO - Biochem Biophys Res Commun VL - 290 UR - https://doi.org/10.1006/bbrc.2001.6169 DO - 10.1006/bbrc.2001.6169 ID - Hatae2002 ER -