Source | KI (4) / (nM) | KI (8) / (μM) |
---|
Bacterial | 100 | 10 |
Rat | 40 | 175 |
Human | 5 | 15 |
- The inhibition constants (KI) were determined from the figures 4 and 5 for 3-hydroxydesaminokynurenine (4) and those for 3-methoxydesaminokynurenine (5) were determined in a similar fashion (graphs not shown).