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Table 2 Functional predictions of high-scoring COGs.

From: Thermophile-specific proteins: the gene product of aq_1292 from Aquifex aeolicus is an NTPase

COG name

Predicted function

COG1618

Predicted nucleotide kinase

COG3635

Predicted phosphoglycerate mutase, AP superfamily

COG1355

Predicted dioxygenase

COG1371

Uncharacterized conserved protein

COG2078

Uncharacterized conserved protein

COG1980

Archaeal fructose 1,6-bisphosphatase

COG1144

Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, delta subunit

COG1820

N-acetylglucosamine-6-phosphate deacetylase

COG1730

Predicted prefoldin, molecular chaperone implicated in de novo protein folding

COG1503

Peptide chain release factor 1 (eRF1)

COG1867

N2, N2-dimethylguanosine tRNA methyltransferase

COG1581

Archaeal DNA-binding protein

COG1888

Uncharacterized protein conserved in archaea

COG1350

Predicted alternative tryptophan synthase beta-subunit (paralog of TrpB)

COG1909

Uncharacterized protein conserved in archaea

COG1110

Reverse gyrase

COG1318

Predicted transcriptional regulators

COG1630

Uncharacterized protein conserved in archaea

COG2250

Uncharacterized conserved protein related to C-terminal domain of eukaryotic chaperone, SACSIN

  1. Descriptions are taken from the current COG-database.