BOH | NAD+ | AcAc | NADH, H+ | ||||
---|---|---|---|---|---|---|---|
Tissue | Physiological states | KM (mM) | KM (mM) | KD (mM) | KM (mM) | KM (mM) | KD (mM) |
Liver | Euthermic(active) | 0.633 ± 0.05 | 0.238 ± 0.015 | 2 ± 0.18 | 0.150 ± 0.01 | 0.074 ± 0.005 | 0.15 ± 0.01 |
Prehibernating | 1.06 ± 0.1 (× 1.67)* | 0.55 ± 0.04 (× 2.3)* | 1.33 ± 0.1 (× 6.8)* | 1.026 ± 0.008 (× 6.8)* | 0.28 ± 0.018 (× 3.8)* | 0.4 ± 0.03 (× 2.66)* | |
Hibernating | 0.944 ± 0.07 (× 1.49)* | 0.174 ± 0.014 (× 0.73)* | 0.444 ± 0.035 (× 0.22)* | 0.146 ± 0.01 (× 0.97) | 0.058 ± 0.005 (× 0.78)* | 0.12 ± 0.01 (× 0.8)* | |
Brain | Euthermic(active) | 2 ± 0.15 | 1.187 ± 0.1 | 1.9 ± 0.1 | 0.216 ± 0.018 | 0.076 ± 0.005 | 0.16 ± 0.01 |
Prehibernating | 2.25 ± 0.2 (× 1.25) | 1.35 ± 0.1 (× 1.13) | 1.72 ± 0.1 (× 0.9) | 0.287 ± 0.02 (× 1.33)* | 0.066 ± 0.004 (× 0.87)* | 0.2 ± 0.0175 (× 1.25)* | |
Hibernating | 1.33 ± 0.12 (× 0.66)* | 0.787 ± 0.06 (× 0.66)* | 3.11 ± 0.25 (× 1.64)* | 0.067 ± 0.004 (× 0.30)* | 0.035 ± 0.002 (× 0.46)* | 0.9 ± 0.06 (× 5.62)* |