Table 1 Variation of BDH activity in both directions (oxidation of BDH and reduction of AcAc) in brain and liver measured at 37°C or 9°C under different physiological conditions. Values are given in nmol/min/mg mitochondrial protein in mean ± standard deviation of at least two experiments with 4 different animals for each condition at *P < 0.05 as compared to the active (A) or at **P < 0.05 as compared to the prehibernator (PH) calculated by ANOVA test.

Liver

AcAc → BOH

37°C

30.65 ± 1.77

14.86 ± 0.8 (× 0.48)*

19.1 ± 2.4 (× 0.62)* (× 1.28)**

42.87 ± 5.9 (× 1.4)* (× 2.88)**

BOH → AcAc

37°C

33.11 ± 4.02

18.8 ± 1.4 (× 0.57)*

27.33 ± 2.7 (× 0.82)* (× 1.45)**

44.1 ± 2 (× 1.33)* (× 2.33)**

BOH → AcAc

9°C

2.08 ± 0.24

-

-

6.84 ± 1.05 (× 3.29)*

Brain

AcAc → BOH

37°C

12.64 ± 1.9

10.33 ± 1.22 (× 0.82)*

8.19 ± 1.76 (× 0.65)* (× 0.79) **

16.11 ± 0.72 (× 1.27)* (× 1.56) **

BOH → AcAc

37°C

5.14 ± 0.16

4.35 ± 0.48 (× 0.85)*

3.05 ± 0.32 (× 0.59)* (× 0.70) **

6.11 ± 0.64 (× 1.19)* (× 1.4) **

BOH → AcAc

9°C

2.54 ± 0.59

-

-

3.33 ± 0.06 (× 1.31)*

ratio

ratio

ratio

ratio

Liver / Brain

BOH → AcAc

37°C

6.4

4.3

8.9

7.2

BOH → AcAc

9°C

0.8

-

-

2.0