Table 1 Kinetic parameters for the hydrolysis of CoA and CoA derivatives by Trx-Y87G2A.14 fusion protein
From: The Caenorhabditis elegans Y87G2A.14 Nudix hydrolase is a peroxisomal coenzyme A diphosphatase
Substrate | Km (mM) | kcat (s-1) | kcat / Km (103M-1.s-1) |
|---|---|---|---|
CoA | 0.22 | 13.8 | 64 |
Acetyl-CoA | 0.23 | 11.8 | 51 |
Succinyl-CoA | 0.24 | 12.7 | 53 |
3-Hydroxymethylglutaryl-CoA | 0.20 | 10.5 | 54 |
CoASSCoA | 0.32 | 2.9 | 9.1 |