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Figure 1 | BMC Biochemistry

Figure 1

From: Delineation of RAID1, the RACK1 interaction domain located within the unique N-terminal region of the cAMP-specific phosphodiesterase, PDE4D5

Figure 1

The unique N-terminal region of PDE4D5 This shows schematically the domain structure of the PDE4D5 long isoform together with the amino acid sequence (GenBankâ„¢ accession number AF012073) of its unique 88 residue N-terminal region. Indicated by a horizontal arrow is the sequence of both the 16-mer and 38-mer peptides that were assessed for binding to RACK1. In bold typeface are shown the residues of the essential Asn-22/Pro-23/Trp-24/Asn-26 grouping and also those that form the essential hydrophobic ridge, Leu-29, Val-30, Leu-33, Leu-37 and Leu-38. Also indicated are the positions of the various truncated species made with associated residue numbers.

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BMC Biochemistry

ISSN: 1471-2091

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