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Table 1 Sequence Comparison of Putative Binding Loop Region.

From: Identification of critical residues in loop E in the 5-HT3ASR binding site

  1. Primary amino acid sequence of representative members of the LGIC superfamily showing amino acid residues on either side of the conserved glycine residue. The amino acids shown span the region from Y140 – P154 of the 5-HT3R. The conserved glycine is shown in bold. Amino acids identified in the binding site of other LGIC subunits and the tyrosines identified in this study are shown in red, bold italics [1117].