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Figure 5 | BMC Biochemistry

Figure 5

From: Gene expression profile of HIV-1 Tat expressing cells: a close interplay between proliferative and differentiation signals

Figure 5

Predictive model for control of gene expression and signal transduction by constitutive Tat expressing cells. Down-regulation of SWI/SNF components such as BAF 170 and 60 along with coactivators CBP/p300 and SRC-1 may down-regulate a subset of cellular genes that depend on chromatin remodeling and/or co-activator function for their gene expression. Such genes depend on the presence of ligand receptors that require either both SRC-1 and p300 or individual co-activator for their activity.

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BMC Biochemistry

ISSN: 1471-2091

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