Plasma lipases and lipid transfer proteins increase phospholipid but not free cholesterol transfer from lipid emulsion to high density lipoproteins.

Table 2 Influence of plasma lipases on the distribution of ¹⁴C-free cholesterol (FC) and ³H-phospholipid (PL) from lipid emulsions to plasma lipoproteins of hepatectomized rats in vivo.

Percent distribution of ¹⁴C-FC and ³H-PL from lipid emulsion to VLDL, LDL and HDL plasma fractions from anesthetized hepatectomized rats treated with saline (control) or heparin after 30 minutes of an intra-arterial injection of the labeled emulsion. Lipoprotein fractions were obtained by ultracentrifugation. Results are expressed as median (range), n=4. Mann-Whitney test for heparin vs. control comparisons: a: ³H-PL - CM+VLDL, p < 0.03; b: ¹⁴C-FC - LDL, p < 0.03; c: ³H-PL - LDL, p < 0.03.

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