Fractions | Control | | Post-heparin | Post-heparin + | THL | |
---|
| 3H-FC | 14C-PL | 3H-FC | 14C-PL | 3H-FC | 14C-PL |
---|
LDL | 15 | 7 | 21 | 7 | 20 | 6 |
| (2-35) | (3-49) | (15-26) | (2-13) | (17-34) | (1-12) |
HDL | 13 | 31a | 18 | 50a,b | 15 | 39a,c |
| (7-28) | (18-47) | (12-36) | (35-68) | (8-33) | (23-48) |
- Percent transfer of 3H-FC and 14C-PL from lipid emulsion to LDL and HDL obtained from fasting human plasma control, post-heparin with and without addition of a lipase inhibitor, tetrahydrolipstatin (THL) incubated for 30 minutes at zero (ice) and at 37°C. Plasma lipoproteins were fractionated by FPLC. Percent transfer was calculated as the difference between values obtained at 37°C and 0°C. Results are expressed as median (range), n=12. Mann-Whitney test: a: p< 0.001 (HDL vs. LDL) ; b: p<0.001 (post-heparin vs. control) and c: p<0.01 (post-heparin vs. post-heparin+THL).