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Table 2 Comparison of inhibitory potential for helicase activity

From: Plasmodium falciparum UvrD activities are downregulated by DNA-interacting compounds and its dsRNA inhibits malaria parasite growth

Compounds

PfUDN

PfH45

PfD66/PfDDX19

PfDH60

Ethidium bromide

4.8

1.0

1.0

1.5

Daunorubicin

3.0

1.5

ND

0.3

Netropsin

4.7

0.5

0.5

1.2

Nogalamycin

3.5

0.5

5.0

2.0

  1. ND- Not determined.
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BMC Biochemistry

ISSN: 1471-2091

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