Skip to main content
Figure 3 | BMC Biochemistry

Figure 3

From: Plasmodium falciparum UvrD activities are downregulated by DNA-interacting compounds and its dsRNA inhibits malaria parasite growth

Figure 3

The effect of different compounds on the DNA unwinding activity of PfUDN. The structure of the DNA helicase substrate is shown on the left side of the autoradiogram of the gel. Lane C is the control without enzyme and lane B is heated substrate. Lane 1 is the control reaction with enzyme without any added compound. Lanes 2–14 are the reactions with enzyme in the presence of different compounds (20 μM) labeled below the autoradiogram. Percent helicase activity of PfUDN in presence of various compounds are presented in the bar diagram corresponding to the autoradiogram.

Back to article page

BMC Biochemistry

ISSN: 1471-2091

Contact us